Browse our latest Computational and Systems Biology articles

Benchmark simulations show that the VEXAT muscle model is more accurate than a Hill-type muscle model at mimicking the response of biological muscle to length changes great and small.

Nearly a thousand diverse adaptive mutants converge into a handful of groups for which fitness responds the same way to environmental change.

ImmCellTyper enhances CyTOF data analysis by combining expert biological knowledge with advanced clustering tools to provide an accurate, comprehensive, and user-friendly solution for high-dimensional immune profiling.

Tronko provides a scalable solution for accurate taxonomic assignment for large-scale metabarcoding datasets by overcoming the speed and memory limitations of previous phylogenetic placement methods.

Identifying, indexing, and annotating molecular dynamics simulations open data is essential to ensure their proper reuse.

A dysregulated circular RNA in bladder cancer controls oncogenic pathways by tethering specific RNA-binding proteins, which in turn inhibits their normal functions.

To investigate why bats are long-lived and cancer-resistant, multi-omic data from bat and human cells was analyzed using computational flux modeling, suggesting dysregulation of succinate-fumarate dynamics and an ischemic-like basal metabolism in bat cells.