Browse our latest Computational and Systems Biology articles

Under conditions where the force of HIV infection per cell is high, partial attenuation of infection with inhibitors can increase the number of live infected cells and may paradoxically be beneficial for viral spread.

The p38 MAPK pathway functions downstream of a cell-size-sensing process to coordinate cell size/growth with G1 progression in animal cells.

Without using control cohorts, a statistical method identifies candidates for immune receptors associated with diseases from repertoire sequencing datasets.

Colony satiation level determines the unloading rate of laden foragers, which, in turn, rely on their own food load to adjust their foraging effort.

Drosophila grooming is driven by two internal programs.

Bayesian integration is able to predict placebo treatment outcomes by focusing especially on the influence of the precision of expectations.

Phosphorylation of Aurora A does not trigger a population shift to the active state as previously thought, but instead switches the kinase on by tuning the structure and dynamics of a dynamically sampled subpopulation.

Statistics on the frequencies of pi interactions in folded protein structures enable successful prediction of intrinsically disordered protein phase separation, with clear implications for a physical understanding of cellular organization.

The extinction of bacterial populations by antibiotics is stochastic and can be predicted only probabilistically, not deterministically.

Epithelial tissue remodeling during Drosophila embryonic development is quantitatively described by a simple law relating myosin activity and cell flow.