Computational and Systems Biology

Latest articles

1. 1. Genetics and Genomics
   2. Computational and Systems Biology

   The impact of ambient contamination on demultiplexing methods for single-nucleus multiome experiments

   Terence Li, Marcus Alvarez ... Noah Zaitlen
2. 1. Neuroscience
   2. Computational and Systems Biology

   Reorganization of spinal neural connectivity following recovery after thoracic spinal cord injury: insights from computational modelling

   Natalia A Shevtsova, Andrew B Lockhart ... Simon M Danner
3. 1. Computational and Systems Biology
   2. Neuroscience

   Homophilic wiring principles underpin neuronal network topology in vitro

   Danyal Akarca, Alexander WE Dunn ... Manuel Schröter
4. 1. Immunology and Inflammation
   2. Computational and Systems Biology

   The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids

   David Saeb, Emma E Lietzke ... Kayla G Sprenger
5. 1. Computational and Systems Biology

   The Product neutrality function defining genetic interactions emerges from mechanistic models of cell growth

   Lucas Fuentes Valenzuela, Paul Francois, Jan Skotheim
6. 1. Neuroscience
   2. Computational and Systems Biology

   Assemblies, synapse clustering, and network topology interact with plasticity to explain structure-function relationships of the cortical connectome

   András Ecker, Daniela Egas Santander ... Michael W Reimann

   A new framework for exploring the mechanisms underlying learning in cortical microcircuits is established.
7. 1. Computational and Systems Biology

   A neuromorphic model of active vision shows how spatiotemporal encoding in lobula neurons can aid pattern recognition in bees

   HaDi MaBouDi, Mark Roper ... James AR Marshall

   Active vision dynamically refines spatiotemporal neural representations, optimising visual processing through scanning behaviour and non-associative learning, providing insights into efficient sensory encoding in dynamic environments.
8. 1. Computational and Systems Biology

   Methylation: Modifying gene expression through passive forces

   Sarah Hallstein, Julian König

   The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.
9. 1. Computational and Systems Biology

   Passive shaping of intra- and intercellular m6A dynamics via mRNA metabolism

   David Dierks, Ran Shachar ... Schraga Schwartz

   A quantitative model explains intra- and intercellular changes in m6A gene methylation as passive consequences of mRNA metabolism.
10. 1. Neuroscience
    2. Computational and Systems Biology

    Individuality transfer: Predicting human decision-making across tasks

    Hiroshi Higashi