Browse our latest Developmental Biology articles

Page 122 of 211
    1. Cell Biology
    2. Developmental Biology

    Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex

    Yue Qu, Ines Hahn ... Andreas Prokop
    The cortical collapse factor Efa6 limits axon growth and branching and maintains axonal microtubule bundle integrity by inhibiting microtubule polymerisation at the cell cortex.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration

    Dana Gancz, Brian C Raftrey ... Karina Yaniv
    Cardiac lymphatic vessels of heterogeneous origins and molecular signatures support cardiac growth and regeneration.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Late developing cardiac lymphatic vasculature supports adult zebrafish heart function and regeneration

    Michael RM Harrison, Xidi Feng ... Ching-Ling Lien
    Zebrafish develop cardiac lymphatic vessels along coronary arteries and this vasculature supports scar reduction following severe damage to the myocardium.
    1. Developmental Biology

    Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4

    Jianlin Liang, Nan Wang ... Kehkooi Kee
    In vitro reprogramming of human fibroblasts to Sertoli-like cells with immunosuppressive properties provides platforms for basic research and clinical application.
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    The Wolbachia cytoplasmic incompatibility enzyme CidB targets nuclear import and protamine-histone exchange factors

    John Frederick Beckmann, Gagan Deep Sharma ... Mark Hochstrasser
    Genetic and proteomic screening with Wolbachia's CidB enzyme reveal the mechanisms and targets of cytoplasmic incompatibility (CI).
    1. Developmental Biology
    2. Neuroscience

    Synaptic mitochondria regulate hair-cell synapse size and function

    Hiu-tung C Wong, Qiuxiang Zhang ... Katie Kindt
    Mitochondrial calcium influx plays distinct roles in presynapse formation, function and stability in sensory hair cells.
    1. Developmental Biology
    2. Evolutionary Biology

    Maternally regulated gastrulation as a source of variation contributing to cavefish forebrain evolution

    Jorge Torres-Paz, Julien Leclercq, Sylvie Rétaux
    Phenotypic evolution can originate from variations in very precocious developmental events, starting even before fecundation, during the fabrication of the egg in the mother's gonad.
    1. Developmental Biology

    Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma

    Benjamin R Thomson, Isabel A Carota ... Susan E Quaggin
    Genetic deletion of one Ptprb allele leads to increased phosphorylation of the TEK receptor, increasing Schlemm's canal area and protecting retinal ganglion cells in a mouse model of glaucoma.
    1. Developmental Biology

    Mask family proteins ANKHD1 and ANKRD17 regulate YAP nuclear import and stability

    Clara Sidor, Nerea Borreguero-Munoz ... Barry J Thompson
    The MASK family of proteins regulate the action of the YAP/TAZ family of transcriptional coactivators, key regulators of stem cell proliferation and cancer.
    1. Cell Biology
    2. Developmental Biology

    Multiplex live single-cell transcriptional analysis demarcates cellular functional heterogeneity

    Ayhan Atmanli, Dongjian Hu ... Ibrahim John Domian
    A novel live-cell mRNA imaging technology identifies individual living cells based on their gene expression and enables the concurrent study of their physiology.