Browse our latest Developmental Biology articles

Page 138 of 211
    1. Developmental Biology
    2. Neuroscience

    Neuroblast-specific open chromatin allows the temporal transcription factor, Hunchback, to bind neuroblast-specific loci

    Sonia Q Sen, Sachin Chanchani ... Chris Q Doe
    Spatial factors generate neuroblast-specific open chromatin, thereby biasing the subsequent binding of transcription factors to produce neuroblast-specific neurons.
    1. Developmental Biology

    Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development

    David AD Munro, Yishay Wineberg ... Jamie A Davies
    Embryonic macrophages encourage early kidney development, interact with developing renal blood vessels, are enriched for mRNAs linked to vascular development, and promote endothelial cross-connections.
    1. Developmental Biology
    2. Neuroscience

    TIAM-1/GEF can shape somatosensory dendrites independently of its GEF activity by regulating F-actin localization

    Leo TH Tang, Carlos A Diaz-Balzac ... Hannes E Bülow
    The DMA-1/LRR-TM cell surface receptor signals through partially redundant pathways to cell-autonomously pattern dendrites, including by directly forming a complex with both the TIAM-1/GEF and ACT-4/Actin.
    1. Developmental Biology

    LncEGFL7OS regulates human angiogenesis by interacting with MAX at the EGFL7/miR-126 locus

    Qinbo Zhou, Bo Yu ... Shusheng Wang
    lncEGFL7OS is a lncRNA located at the EGFL7/miR-126 locus that is critical for angiogenesis in humans.
    1. Developmental Biology
    2. Neuroscience

    Embryonic Development: The evolution of hearing and balance

    Forrest P Weghorst, Karina S Cramer
    New genetic tools have allowed researchers to compare how the brainstem auditory and vestibular nuclei develop in embryonic chicks and mice.
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    1. Developmental Biology

    Species-specific maturation profiles of human, chimpanzee and bonobo neural cells

    Maria C Marchetto, Branka Hrvoj-Mihic ... Fred H Gage
    Using iPSCs as a model to study neurodevelopmental differences between human and nonhuman primates lays the groundwork for understanding aspects of human brain evolution and neurological disease susceptibility.
    1. Cell Biology
    2. Developmental Biology

    Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration

    Daniel Čapek, Michael Smutny ... Carl-Philipp Heisenberg
    Uniform activation of Frizzled7 signaling is required and sufficient for directional mesendoderm cell migration during zebrafish gastrulation.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Nephron progenitor commitment is a stochastic process influenced by cell migration

    Kynan T Lawlor, Luke Zappia ... Alexander N Combes
    Stochastic cell migration modulates exposure to signals that regulate commitment in the nephron progenitor niche.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    scRNA-Seq reveals distinct stem cell populations that drive hair cell regeneration after loss of Fgf and Notch signaling

    Mark E Lush, Daniel C Diaz ... Tatjana Piotrowski
    Several support cell populations balance progenitor maintenance with differentiation in zebrafish lateral line sensory organs.
    1. Developmental Biology
    2. Neuroscience

    Synapse maintenance is impacted by ATAT-2 tubulin acetyltransferase activity and the RPM-1 signaling hub

    Melissa A Borgen, Andrew C Giles ... Brock Grill
    Genetic, developmental and pharmacological analysis in Caenorhabditis elegans demonstrate that ATAT-2 tubulin acetyltransferase activity regulates synapse maintenance by acting within the RPM-1 signaling network, but independent of the DLK-1 MAP3K.