Browse our latest Developmental Biology articles

Page 137 of 209
    1. Cell Biology
    2. Developmental Biology

    Mechanotransduction: How muscle contraction strengthens tendons

    Nicole O Glenn, Clarissa A Henry
    The force generated by muscles leads to signaling that helps to shape nearby tendon precursor cells.
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    1. Developmental Biology

    Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling

    Kerim B Kaylan, Ian C Berg ... Gregory H Underhill
    Mechanical stress plays a cooperative role with Notch in biliary differentiation of liver progenitors, supporting a model of liver development in which biomechanical cues are key inducers of cell fate.
    1. Developmental Biology
    2. Plant Biology

    Quantitative analysis of auxin sensing in leaf primordia argues against proposed role in regulating leaf dorsoventrality

    Neha Bhatia, Henrik Åhl ... Marcus G Heisler
    Top-bottom patterning of leaves is not specified by an asymmetry in the distribution of the plant hormone auxin, in contrast to a previous proposal.
    1. Developmental Biology

    Primed Track, high-fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins

    Maaike Welling, Manuel Alexander Mohr ... Periklis Pantazis
    Primed Track is an image analysis tool that allows for computational correction of drifting specimen to enable accurate lineage tracing of mammalian pre-implantation development even for larger imaging time intervals.
    1. Developmental Biology
    2. Physics of Living Systems

    Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain

    Amelia J Thompson, Eva K Pillai ... Kristian Franze
    During embryonic development, tissue stiffness, which provides an important signal to motile cells, changes locally within tens of minutes in a well-controlled manner.
    1. Developmental Biology

    The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling

    Seyed Javad Rasouli, Mohamed El-Brolosy ... Didier Y Stainier
    Endocardial Klf2 regulates cardiomyocyte adhesion and myocardial wall integrity by modulating FGF signaling in zebrafish.
    1. Computational and Systems Biology
    2. Developmental Biology

    A re-inducible gap gene cascade patterns the anterior–posterior axis of insects in a threshold-free fashion

    Alena Boos, Jutta Distler ... Ezzat El-Sherif
    The body axis of insects is divided into different fates using a self-regulatory and threshold-free mechanism.
    1. Developmental Biology
    2. Neuroscience

    Tuning of delta-protocadherin adhesion through combinatorial diversity

    Adam J Bisogni, Shila Ghazanfar ... David M Lin
    Combinatorial expression patterns of δ-Pcdhs are defined within single neurons, and in vitro assays are employed to establish guiding principles used by this gene family to mediate cell adhesion.
    1. Developmental Biology

    Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers

    Nanoka Suzuki, Kodai Hirano ... Haruki Ochi
    Arid3a, a component of H3K9 me3 demethylases, regulates regeneration of the proximal nephric tubule through the evolutionarily conserved regeneration signal-response enhancer.
    1. Developmental Biology

    Spatiotemporally controlled genetic perturbation for efficient large-scale studies of cell non-autonomous effects

    Andrea Chai, Ana M Mateus ... Rita Sousa-Nunes
    A novel genetic strategy for induction of reproducible neural tumors (or any other deleterious phenotype) in a single Drosophila stock (applicable to other organisms).