Browse our latest Developmental Biology articles

Differences in the activity of an enzyme called CARM1 influence the timing of blastomere polarization and whether they become part of the embryo or the placenta.

Rewiring the command neurons in the tactile circuit is sufficient to change the behavioral strategy of a whole animal, implying a 'plug-and-play' flexibility in sensorimotor circuits.

Targeting Atoh1 for CRISPR/Cas9-mediated mutagenesis in sturgeon results in missing electroreceptors as well as mechanosensory hair cells, supporting conserved developmental mechanisms, whereas ectopic electrosensory organs develop after targeting mechanosensory-restricted Foxg1, suggesting FoxG1 directly or indirectly represses electrosensory organ formation.

Sulfation is required for organizing the apical extracellular matrix during tubular organ formation.

An organoid-based screening platform that allows one-gene-at-a-time knockdown across a whole tissue has been used to identify the genes that regulate closure of the neural tube in humans.

Changes of the chromatin structure suggests how the fate selector transcription factors are activated and how they guide differentiation of GABAergic and glutamatergic neurons in the anterior brainstem.

Bioluminescence imaging in live mice was used to assess the abilities of systemically introduced adeno-associated viral capsids containing enhancer regulatory sequences to target transgene expression to myocardial injuries.

The hemogenic gastruloid model of embryonic blood development captures multi-wave haematopoiesis and enables interrogation of infant leukaemia cell-of-origin.