Kawsar Hossain, Madeline Smith ... Stephen W Santoro
The neurogenesis rates of some olfactory sensory neuron subtypes are selectively accelerated in mice that are exposed to odors that stimulate those subtypes.
Transgenic and pharmacological approaches reveal developmental elevations in glycolytic flux have an instructive role in promoting rod photoreceptor differentiation and maturation via activation of Wnt signaling.
The blueprint and narrative of shape formation during early development can be objectively observed by quantifying and analyzing whole-embryo dynamics.
Haley N Mendoza-Romero, Jessica E Biddinger ... Richard Simerly
Hypothalamic microglia play an essential role in mediating changes to feeding circuitry caused by exposure to maternal HFD that may contribute to developmental programming of metabolic phenotype.
BCAS2 directly binds to the Armadillo repeats 9–12 of β-catenin via the coiled-coil domains, sequestering β-catenin within the nucleus and thereby promoting Wnt signaling during primitive hematopoiesis.
A temporally stable and cell-type-specific genetic driver library provides the means to access and manipulate neuronal lineages in the fly nervous system during development and adulthood.
Daniel de la Fuente, Maria Maroto ... Alfonso Gutierrez-Adan
The oocyte zona pellucida needs to interact with an oviduct protein called OVGP1 to ensure that only sperm from the same species can fertilize the egg.