Browse our latest Developmental Biology articles

A transcription factor called SALL4 could be the missing link between thalidomide and the limb defects caused by the drug.

Analysis of the endogenous function of deeply conserved neuropeptides in sea anemones sheds light on a primitive role of nervous systems in modulating developmental timing.

High levels of nuclear YAP are sufficient to drive squamous cell carincoma formation and frequently also drive progression to spindle cell carcinoma by promoting epithelial-to-mesenchymal transition after tissue damage.

Size control in limbs is an intrinsically determined process.

Free, extracellular dispersal of Wnt proteins generates a long-range gradient during animal development and is required for signaling.

A nerve bundle is not simply a cable of wires, but has order within it.

An under-studied microtubule-associated protein is found to regulate axon growth and branching by modulating microtubule-based organelle transport through its dual interactions with microtubules and the conventional kinesin motor.

Ploidy-increasing endocycles may represent a tradeoff between loss of regenerative capacity and preservation of tissue architecture.

Rather than acting as passive and neutral co-factors for proneural proteins, E proteins play an active role in modulating the way the distinct proneural proteins instruct neurogenesis.

T cell progenitor homing into the thymus requires kindlin-3 to stabilize their adhesion to vascular integrin ligands when blood flow velocities and shear rates increase during development.