Browse our latest Developmental Biology articles

Page 142 of 211
    1. Developmental Biology

    A novel mechanism of gland formation in zebrafish involving transdifferentiation of renal epithelial cells and live cell extrusion

    Richard W Naylor, Hao-Han G Chang ... Alan J Davidson
    A rare example of direct transdifferentiation is discovered in zebrafish in which kidney epithelial cells change into an endocrine gland and undergo live-cell extrusion from the renal tubule.
    1. Developmental Biology
    2. Genetics and Genomics

    Zygotic gene activation in the chicken occurs in two waves, the first involving only maternally derived genes

    Young Sun Hwang, Minseok Seo ... Jae Yong Han
    In Aves, the first wave of transcription is derived exclusively from the maternal genome.
    1. Cell Biology
    2. Developmental Biology

    Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retina

    Harri Elamaa, Minna Kihlström ... Lauri Eklund
    Identification of importance of Angiopoietin-4 (Angpt4) as a first growth factor that initiates venous specification in the peripheral retina, and Angpt4-dependent mechanism for fluid clearance in the mouse retina.
    1. Cell Biology
    2. Developmental Biology

    Shear-induced damped oscillations in an epithelium depend on actomyosin contraction and E-cadherin cell adhesion

    Ehsan Sadeghipour, Miguel A Garcia ... Beth L Pruitt
    Cell movement toward and away from the midline of an epithelium over tens of hours are caused by spontaneous or externally-applied shear forces to eliminate force imbalances within the tissue.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids

    Anna Yoney, Fred Etoc ... Ali H Brivanlou
    The requirement for WNT signaling in mesendoderm differentiation is temporally separate from that of ACTIVIN signaling and acts to switch the output of ACTIVIN/SMAD2 from pluripotency maintenance to mesendoderm patterning.
    1. Computational and Systems Biology
    2. Developmental Biology

    A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment

    Kenneth KH Ng, Mary A Yui ... Hao Yuan Kueh
    The timing and outcome of mammalian cell lineage decisions can be controlled by slow, stochastic events on individual regulatory gene loci.
    1. Developmental Biology
    2. Evolutionary Biology

    Decoupling from yolk sac is required for extraembryonic tissue spreading in the scuttle fly Megaselia abdita

    Francesca Caroti, Everardo González Avalos ... Steffen Lemke
    Extraembryonic tissue spreading in the scuttle fly Megaselia abdita requires mechanical decoupling from the underlying yolk sac.
    1. Stem Cells and Regenerative Medicine
    2. Developmental Biology

    Hair follicle epidermal stem cells define a niche for tactile sensation

    Chun-Chun Cheng, Ko Tsutsui ... Hironobu Fujiwara
    Heterogeneous epidermal stem cells define a niche for tactile sensation via providing a unique ECM and tissue architecture for nerves, revealing their new functions in coordinated sensory organ formation.
    1. Computational and Systems Biology
    2. Developmental Biology

    Tuned polymerization of the transcription factor Yan limits off-DNA sequestration to confer context-specific repression

    C Matthew Hope, Jemma L Webber ... Ilaria Rebay
    Tuned protein–protein interaction affinity optimizes the repressive function of the ETS family transcription factor Yan in order to contribute specificity and robustness to cell fate specification in the developing Drosophila eye.
    1. Developmental Biology

    Feedback regulation of cytoneme-mediated transport shapes a tissue-specific FGF morphogen gradient

    Lijuan Du, Alex Sohr ... Sougata Roy
    FGF morphogen gradient self-generates a recipient tissue-specific contour by feedback-regulating its cytoneme-mediated dispersion.