Nereo Kalebic, Carlotta Gilardi ... Wieland B Huttner
Expression of human-specific gene ARHGAP11B in the developing ferret neocortex leads to an increase in abundance of neural progenitor cells, which results in neocortex expansion.
The demand for robust performance distinguishes the mechanism which progresses the biological timer acting within neural progenitors to determine neuronal fates in the Drosophila embryo.
HIPPO signaling antagonizes the apical domain of polarized cells, driving cell internalization, regulated gene expression, and cell fate change during formation of pluripotent stem cell progenitors in the mouse embryo.
Biological shapes and morphological transitions can emerge from combining directed interactions between cells with apical-basal and planar cell polarity.
Joseph M Chambers, Shahram Jevin Poureetezadi ... Rebecca A Wingert
The transcriptional coactivator ppargc1a regulates the renal progenitor patterning to delineate boundary formation of differentiated segment populations during nephrogenesis.
Abbey C Thompson, Terence D Capellini ... David M Kingsley
Regulatory sequences downstream of a key limb identity gene are required for normal sizes of leg bones, and are changed in wild species with dramatic alterations in pelvic structures.
