Browse our latest Developmental Biology articles

Page 50 of 209
    1. Developmental Biology
    2. Physics of Living Systems

    On the origin of universal cell shape variability in confluent epithelial monolayers

    Souvik Sadhukhan, Saroj Kumar Nandi
    The nearly universal nature of scaled cell shape variability in an epithelial monolayer is unavoidable, irrespective of health or disease, as it comes from a mathematical property.
    1. Developmental Biology
    2. Evolutionary Biology

    Vocal communication is tied to interpersonal arousal coupling in caregiver-infant dyads

    Sam Wass, Emily Phillips ... Louise Goupil
    Infants' vocalisations are contingent on their own stress physiology, and alter the inter-personal dynamics of how stress states are shared across the infant-caregiver dyad.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Transcriptional profiling of Hutchinson-Gilford Progeria syndrome fibroblasts reveals deficits in mesenchymal stem cell commitment to differentiation related to early events in endochondral ossification

    Rebeca San Martin, Priyojit Das ... Rachel Patton McCord
    Age-stratified comparisons of gene expression in progeria patient fibroblasts reveals disruption of mesenchymal lineage pathways and points to a deficit in chondrogenic commitment in early development and a depletion of the mesenchymal lineage stem cell pool.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Germline/soma distinction in Drosophila embryos requires regulators of zygotic genome activation

    Megan M Colonnetta, Paul Schedl, Girish Deshpande
    Components of zygotic genome activation, Zelda and CLAMP, contribute to the proper specification of primordial germ cells in Drosophila embryos.
    1. Cell Biology
    2. Developmental Biology

    Aurora A and cortical flows promote polarization and cytokinesis by inducing asymmetric ECT-2 accumulation

    Katrina M Longhini, Michael Glotzer
    Centrosomal Aurora A (AIR-1), together with cortical actomyosin flows, induces polarization of ECT-2, the activator of RHO-1, during polarization and cytokinesis, in order to promote furrow formation.
    1. Developmental Biology

    Glycolytic flux-signaling controls mouse embryo mesoderm development

    Hidenobu Miyazawa, Marteinn T Snaebjornsson ... Alexander Aulehla
    The functional link between glycolytic flux, cell signalling and mesoderm patterning is investigated in mouse embryo.
    1. Developmental Biology
    2. Medicine

    Meta-Research: The need for more research into reproductive health and disease

    Natalie D Mercuri, Brian J Cox
    An analysis of publications and research grants shows that the volume of research on reproductive organs is much less than that on non-reproductive organs.
    1. Developmental Biology

    TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development

    Jifan Feng, Xia Han ... Yang Chai
    Unbiased single-cell RNAseq data analysis combined with mouse genetic approaches reveal that TGF-β signaling and perimysial-specific regulators may cooperatively define perimysial-to-myogenic signals in regulating pharyngeal myogenesis.
    1. Developmental Biology

    Inhibition of β1-AR/Gαs signaling promotes cardiomyocyte proliferation in juvenile mice through activation of RhoA-YAP axis

    Masahide Sakabe, Michael Thompson ... Mei Xin
    Pharmacological and genetic blockade of β1-AR-Gαs signaling prolongs the cardiac regenerative window in juvenile mouse by activating YAP.
    1. Developmental Biology
    2. Plant Biology

    Opposite polarity programs regulate asymmetric subsidiary cell divisions in grasses

    Dan Zhang, Roxane P Spiegelhalder ... Michael T Raissig
    The formation of stomatal 'helper cells' (=subsidiary cells) in grasses requires two opposing polarity domains with diverse roles in establishing division asymmetry.