Browse our latest Developmental Biology articles

Endothelial cells from separate cardiac lineages start off in distinct transcriptional states, but over the course of development converge into transcriptional and functional states which are unrelated to lineage and which are conserved between mouse and human.

Activation of Wnt/β-catenin signaling in endothelial progenitors derived from human pluripotent stem cells partially induces the specialized blood–brain barrier phenotype while the same treatment in matured endothelial cells is less efficacious.

Cholesterol accessibility in the plasma membrane can be controlled by proteins and function as a signaling messenger in cell-cell communication pathways.

Genetic and imaging analysis reveal that microglial precursors use ocular blood vessels as a pathway to enter the optic cup and subsequently infiltrate the retina preferentially through the neurogenic region.

IL-6 gene and protein expression are rapidly and transiently upregulated in the choroid in response to myopic defocus, as a result of prior form deprivation or treatment with +15 D lenses in a nitric oxide-dependent manner.

A combination of mRNA sequencing and genetic analysis reveals mechanisms that govern the development of distinct differentiated blood cell types from hematopoietic progenitors.

Stress fibers with multiple adhesions along their lengths and treadmilling dynamics may help migrating epithelial cells maintain a linear trajectory and thereby reinforce their collective motility.

Socially exchanged fluids passed mouth-to-mouth in ant colonies contain protein signatures of colony maturity and individual behavioral role, indicating that this fluid may underlie a distributed metabolism that functions over the scale of the colony.

A new method for quantitative assessment of altered regulatory potential of human enhancers bearing disease-associated mutations using live imaging in zebrafish embryos.

During the morphogenesis of the tubes of the salivary glands in the fly embryo, a correct regionalization of the flat epithelial primordium by upstream transcription factors is key to drive coordinated changes in cell behavior.