Browse our latest Developmental Biology articles

Page 75 of 214
    1. Developmental Biology
    2. Neuroscience

    Myelinating Schwann cells and Netrin-1 control intra-nervous vascularization of the developing mouse sciatic nerve

    Sonia Taïb, Noël Lamandé ... Isabelle Brunet
    Angiogenesis and vascular development within peripheral nerve is regulated by Netrin-1, Schwann cells, and myelination.
    1. Developmental Biology

    ZAF, the first open source fully automated feeder for aquatic facilities

    Merlin Lange, AhmetCan Solak ... Loïc Alain Royer
    ZAF (Zebrafish Automated Feeder) is the first fully automated, easy to build, and open source fish feeder designed for small and medium sized labs of which there are an estimated 3250 in 100 countries working with Zebrafish alone today.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos

    Graham JM Hickey, Candice L Wike ... Bradley R Cairns
    Zebrafish early embryos initially package their developmental genes and enhancers in 'active' chromatin that subsequently receives polycomb repressive complex 1 (PRC1)-mediated histone H2A ubiquitylation, which confers silencing/poising – prior to Aebp2-PRC2-guided H3K27me3 addition.
    1. Developmental Biology
    2. Evolutionary Biology

    Cavefish cope with environmental hypoxia by developing more erythrocytes and overexpression of hypoxia-inducible genes

    Corine M van der Weele, William R Jeffery
    Astyanax mexicanus cavefish cope with hypoxic environments by expanding embryonic hematopoietic domains, increasing the capacity for erythrocyte development, and constitutive overexpression of hypoxia-inducible genes.
    1. Cell Biology
    2. Developmental Biology

    Autophagosomes fuse to phagosomes and facilitate the degradation of apoptotic cells in Caenorhabditis elegans

    Omar Peña-Ramos, Lucia Chiao ... Zheng Zhou
    The crosstalk between autophagy and the phagocytosis of apoptotic cells, two cellular clearance pathways, promotes the fusion of the double-membrane autophagosomes to the phagosomes and plays an important role in the degradation of engulfed apoptotic cells.
    1. Developmental Biology
    2. Neuroscience

    PRC1 sustains the integrity of neural fate in the absence of PRC2 function

    Ayana Sawai, Sarah Pfennig ... Jeremy S Dasen
    Regulation of neuronal diversity and fate through protein complexes involved in gene repression and chromatin condensation.
    1. Developmental Biology
    2. Neuroscience

    insomniac links the development and function of a sleep-regulatory circuit

    Qiuling Li, Hyunsoo Jang ... Nicholas Stavropoulos
    Spatiotemporal manipulations of insomniac reveal that this gene regulates the birth and development of sleep-regulatory neurons, enabling their proper function in adulthood.
    1. Developmental Biology
    2. Genetics and Genomics

    Drosophila p53 isoforms have overlapping and distinct functions in germline genome integrity and oocyte quality control

    Ananya Chakravarti, Heshani N Thirimanne ... Brian R Calvi
    Drosophila p53 protein isoforms function during oogenesis to ensure the integrity of the transmitted genome, a function that is conserved to humans.
    1. Developmental Biology
    2. Neuroscience

    Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neurons

    David Sokolov, Emily R Sechrest ... Saravanan Kolandaivelu
    NMNAT1, a ubiquitously expressed metabolic enzyme linked to inherited blinding disease, is crucial for the proper differentiation of photoreceptor cells and subsequent survival of multiple cell types in the retina.
    1. Cell Biology
    2. Developmental Biology

    Nano-scale architecture of blood-brain barrier tight-junctions

    Esther Sasson, Shira Anzi ... Ayal Ben-Zvi
    Super-resolution imaging uncovers sparse occludin vs. clustered ZO1/claudin-5 architecture, and claudin-5 arrangement compacting during blood-brain-barrier tight-junction (TJ) maturation in which TJs become first restrictive to large and later to small molecules.