Browse our latest Developmental Biology articles

A new method for quantitative assessment of altered regulatory potential of human enhancers bearing disease-associated mutations using live imaging in zebrafish embryos.

During the morphogenesis of the tubes of the salivary glands in the fly embryo, a correct regionalization of the flat epithelial primordium by upstream transcription factors is key to drive coordinated changes in cell behavior.

A new zebrafish RBC aggregation model is developed to explore the dynamic process and the underlying regulatory mechanisms in blood clot formation.

Plant meristem size and shape is controlled by two intertwined regional feedback signals that are mediated by secreted peptides.

Reactive oxygen species can activate the ATR/Chk1 pathway in the absence of detectable DNA damage and without a requirement for DNA damage response proteins.

Drosophila females store more fat than males because the presence of a functional Transformer protein in females limits adipokinetic hormone production and pathway activity.

Using single nucleus RNA sequencing, a complete catalogue of cell types was determined for the mouse iris, and this information was used as a starting point to define the effects of pupil dilation on gene expression and on nuclear morphology.

Genetic analysis identifies the origins of midface defects in mouse models of ciliopathies, revealing a role for ciliary Hedgehog signaling in cell survival.

Comprehensive mouse genetic analyses show, by having mTORC1 constitutively active, a RPC divides and exhausts mitotic capacity faster than neighboring RPCs, and thus produces retinal cells that degenerate with aging-related changes in the mature mouse retina.

The 3D shape and dynamic organization of epithelial cells are far more complex than previously believed, but can be explained with simple physical principles based on lateral surface energy minimisation.