A polarized Moody/protein kinase A pathway plays an unrecognized central role in controlling the enormous cell growth and blood–brain barrier integrity in a highly coordinated spatiotemporal manner in brain homeostasis.
Rheological properties of the environment regulate sperm swimming and navigational behavior through suppression or reactivation of sperm rolling around its longitudinal axis.
Filomena Caccavale, Giovanni Annona ... Salvatore D'Aniello
Previously undescribed morphogenetic and developmental mechanisms unravel that the cooperation of two ancient signaling pathways, nitric oxide and retinoic acid, is essential to build a chordate embryo.
Delivery of Hedgehog, Decapentaplegic and Wingless to target cells in the Drosophila wing imaginal disc is regulated in both amount and destination, and is not dependent on constitutive release or uptake from a common pool.
Mice doubly deficient for Naa10 and Naa12 display embryonic lethality, with both enzymes compensating for each other with amino-terminal acetylation of proteins in mouse development.
Image3C is a new image-based analysis of cell population composition for research organisms in which detailed cellular phenotypes are unknown or for which species-specific reagents are not available.