Browse our latest Evolutionary Biology articles

Page 44 of 113
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Heterogeneity of the GFP fitness landscape and data-driven protein design

    Louisa Gonzalez Somermeyer, Aubin Fleiss ... Fyodor A Kondrashov
    Orthologous proteins display different mutational robustness that can be leveraged to improve prediction of functional sequences.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Functional and structural segregation of overlapping helices in HIV-1

    Maliheh Safari, Bhargavi Jayaraman ... Alan D Frankel
    The HIV proteins Env and Rev encode helices that overlap in the viral genome but alternate in functional importance so that the non-functional surface of one helix encodes the functional surface of the other.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Machine Learning: Lighting up protein design

    Grzegorz Kudla, Marcin Plech
    Using a neural network to predict how green fluorescent proteins respond to genetic mutations illuminates properties that could help design new proteins.
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    1. Evolutionary Biology
    2. Genetics and Genomics

    Genetic variation in ALDH4A1 is associated with muscle health over the lifespan and across species

    Osvaldo Villa, Nicole L Stuhr ... Sean P Curran
    Leveraging the US Health and Retirement Study and C. elegans genetics reveals ALDH4A1/alh-6 as an evolutionarily conserved biomarker for normal muscle function over the lifespan.
    1. Evolutionary Biology

    A meta-analysis of the association between male dimorphism and fitness outcomes in humans

    Linda H Lidborg, Catharine Penelope Cross, Lynda G Boothroyd
    While men’s mating success is predicted both by their strength/muscularity, voice pitch, height, and testosterone levels, their reproductive output is only predicted by strength/muscularity.
    1. Evolutionary Biology

    Functional characterization of a ‘plant-like’ HYL1 homolog in the cnidarian Nematostella vectensis indicates a conserved involvement in microRNA biogenesis

    Abhinandan M Tripathi, Yael Admoni ... Yehu Moran
    Presence of a functional homolog of HYL1 in Nematostella vectensis, a basal animal model, indicates divergent evolution of miRNA biogenesis pathway in plants and animals from an ancestral miRNA system.
    1. Evolutionary Biology

    Modeling the consequences of the dikaryotic life cycle of mushroom-forming fungi on genomic conflict

    Benjamin Auxier, Tamás L Czárán, Duur K Aanen
    Fungi that produce mushrooms have a unique life cycle with two haploid nuclei, instead of a diploid nucleus, this allows additional matings and selection at the level of the nucleus, even with a fitness trade-off.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Parent-of-origin effects propagate through networks to shape metabolic traits

    Juan F Macias-Velasco, Celine L St Pierre ... Heather A Lawson
    Non-imprinted genes can contribute to parent-of-origin effects on phenotype through interactions with imprinted genes.
    1. Evolutionary Biology

    Computed tomographic analysis of the dental system of three Jurassic ceratopsians and implications for the evolution of tooth replacement pattern and diet in early-diverging ceratopsians

    Jinfeng Hu, Catherine A Forster ... Fenglu Han
    The tooth replacement pattern of early-diverging ceratopsians helps to understand the origin of the specialized dental system of ceratopsids and provides new insights to feeding strategy transition.
    1. Evolutionary Biology

    The Jurassic rise of squamates as supported by lepidosaur disparity and evolutionary rates

    Arnau Bolet, Thomas L Stubbs ... Michael J Benton
    Evidence for a largely unexplored radiation of squamates (lizards, snakes, and amphisbaenians) in the Middle to Late Jurassic is revealed by analyses of morphospace expansion, disparity, and evolutionary rates.