Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Cancer Biology

   Rearrangement of 3D genome organization in breast cancer epithelial - mesenchymal transition and metastasis organotropism

   Priyojit Das, Rebeca San Martin ... Rachel Patton McCord
2. 1. Chromosomes and Gene Expression

   SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing

   Ashwin Govindan, Nicholas K Conrad
3. 1. Cell Biology
   2. Chromosomes and Gene Expression

   TPR is required for cytoplasmic chromatin fragment formation during senescence

   Bethany M Bartlett, Yatendra Kumar ... Wendy A Bickmore

   Evidence is provided suggesting that heterochromatin re-organisation during cell senescence can compromise the structural integrity of the nucleus, leading to activation of an inflammatory process.
4. 1. Chromosomes and Gene Expression
   2. Evolutionary Biology

   The emergence and evolution of gene expression in genome regions replete with regulatory motifs

   Timothy Fuqua, Yiqiao Sun, Andreas Wagner

   Mutagenizing sequences enriched with promoter motifs creates gene expression de novo, and helps to understand promoter logic, regulatory evolution, and the birth of de novo genes.
5. 1. Chromosomes and Gene Expression
   2. Developmental Biology

   N-terminus of Drosophila melanogaster MSL1 is critical for dosage compensation

   Valentin Babosha, Natalia Klimenko ... Oksana Maksimenko

   N‑terminus of MSL1 protein, involved in dosage compensation in Drosophila, is required for the interaction with non-coding roX2 RNA and the assembly of the complex on the male X chromosome.
6. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping model

   Arkadiy K Golov, Alexey A Gavrilov ... Sergey V Razin

   A new genomic method called MChIP-C measures H3K4me3-associated chromatin interactions with extremely high resolution and sensitivity, detecting interactions in over 60% of functionally verified enhancer-promoter pairs.
7. 1. Developmental Biology
   2. Chromosomes and Gene Expression

   Drosophila Hamlet mediates epithelial tissue assembly of the reproductive system

   Huazhen Wang, Ludivine Bertonnier-Brouty ... Qi Dai
8. 1. Chromosomes and Gene Expression

   Prolonged cell cycle arrest in response to DNA damage in yeast requires the maintenance of DNA damage signaling and the spindle assembly checkpoint

   Felix Y Zhou, David P Waterman ... James E Haber

   Cell cycle arrest in response to a double-stranded break is initially maintained by the DNA damage checkpoint and later by the spindle assembly checkpoint.
9. 1. Chromosomes and Gene Expression

   Decapping activators Edc3 and Scd6 act redundantly with Dhh1 in post-transcriptional repression of starvation-induced pathways

   Rakesh Kumar, Fan Zhang ... Alan G Hinnebusch
10. 1. Chromosomes and Gene Expression
    2. Developmental Biology

    Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos

    Marius Regin, Yingnan Lei ... Claudia Spits

    Aneuploid human embryonic cells are eliminated by p53-mediated apoptosis in a gene dosage dependent manner.