Chromosomes and Gene Expression

Latest articles

1. 1. Developmental Biology
   2. Chromosomes and Gene Expression

   The long-range gene regulatory landscape of cerebellar granule neuron progenitors

   Kimberley LH Riegman, Charlotte George ... M Albert Basson
2. 1. Chromosomes and Gene Expression

   mRNA Imprinting: transcription apparatus can remotely control cytoplasmic post-transcriptional mechanisms by dozens of proteins

   Shira Urim, Artyom Artamov ... Mordechai Choder
3. 1. Chromosomes and Gene Expression
   2. Immunology and Inflammation

   The long non-coding RNA Dreg1 is required for optimal ILC2 development

   Sara Quon, Adelynn Tang ... Rhys S Allan
4. 1. Developmental Biology
   2. Chromosomes and Gene Expression

   Lineage priming and cell type proportioning depends on the interplay between stochastic and deterministic factors

   William M Salvidge, Chris Brimson ... Christopher RL Thompson
5. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   Epigenetics and chromatin structure regulate var2csa expression and the placental-binding phenotype in Plasmodium falciparum

   Todd Lenz, Madle Sirel ... Ulf Ribacke

   Placenta-binding parasites show that chromatin-based mechanisms regulate placental malaria virulence gene, var2csa, and requires loss of H3K9me3-mediated heterochromatic silencing and 3D nuclear repositioning away from telomeric-repressive clusters.
6. 1. Chromosomes and Gene Expression

   TAD boundaries and gene activity are uncoupled

   Faisal Almansour, Nadezda A Fursova ... Tom Misteli

   Single-cell analysis fails to find a functional link between the organization of chromatin domain organization and gene activity.
7. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   Single-cell RNA-seq reveals trans-sialidase-like superfamily gene expression heterogeneity in Trypanosoma cruzi populations

   Lucas Inchausti, Lucia Bilbao ... Pablo Smircich

   Transcriptomic heterogeneity in infective-stage surface proteins of Trypanosoma cruzi, particularly trans-sialidase-like superfamily members, suggests distinct expression profiles among individual parasites that may enhance immune evasion and infection adaptability.
8. 1. Chromosomes and Gene Expression
   2. Computational and Systems Biology

   DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci

   Yuzhen Liu, Christopher D McGann ... Devin K Schweppe

   DNA O-MAP enables proximity labeling at specific genomic loci in fixed cells using programmable oligonucleotides, revealing locus-proximal proteomes and chromatin interactions without genetic modification.
9. 1. Chromosomes and Gene Expression
   2. Computational and Systems Biology

   Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling

   Caleb Hallinan, Hyun Joo Ji ... Jean Fan
10. 1. Chromosomes and Gene Expression

    Interplay between cohesin and TORC1 links chromosome segregation and gene expression to environmental changes

    Dorian Besson, Sabine Vaur ... Jean-Paul Javerzat