Oliver Vöcking, Ioannis Kourtesis ... Harald Hausen
The recently characterized opsin group of xenopsins is likely a major player in animal eye evolution and may have been present in an ancient, highly plastic eye photoreceptor cell type.
Gillian Morven Belbin, Jacqueline Odgis ... Eimear E Kenny
A health-system embedding method for genomic discovery and clinical characterization of disease highlights the importance of documenting a wider spectrum of genetic disorders in diverse populations.
A genetic program controlling brain genes across the lifespan specifies a calendar of changes in cells, synapses and behavioural genes thereby timing the onset of mental illnesses which arise in young adults.
Elizabeth R Jerison, Sergey Kryazhimskiy ... Michael M Desai
Substantial heritable genetic variation in adaptability and the pleiotropic consequences of adaptation exists in budding yeast, and can be explained by a combination of fitness and specific segregating alleles.
Fanny Pouyet, Dominique Mouchiroud ... Marie Sémon
Variation in codon usage among functional categories of human genes is not due to selection for translation efficiency, but to differences in intragenic recombination rate, linked to variation in meiotic transcription level.
John A Lees, Nicholas J Croucher ... Stephen D Bentley
Sequence changes in the pneumococcal genome explain most of the variability in duration of asymptomatic carriage with serotype, antibiotic resistance and prophage accounting for the largest effects.
Xavier Grau-Bové, Guifré Torruella ... Iñaki Ruiz-Trillo
The foundations of genomic complexity in multicellular animals have deep roots in their unicellular prehistory, both in terms of innovations in gene content, as well as the evolutionary dynamics of genome architecture.