Browse our latest Genetics and Genomics articles

Page 127 of 143
    1. Genetics and Genomics
    2. Plant Biology

    The genome and phenome of the green alga Chloroidium sp. UTEX 3007 reveal adaptive traits for desert acclimatization

    David R Nelson, Basel Khraiwesh ... Kourosh Salehi-Ashtiani
    Euryhaline green algae utilise intracellular osmoprotectant modulation and specialised redox enzyme networks to successfully inhabit a desert coastline.
    1. Genetics and Genomics

    Pervasive epigenetic effects of Drosophila euchromatic transposable elements impact their evolution

    Yuh Chwen G Lee, Gary H Karpen
    The ability of transposable elements to epigenetically influence adjacent genes impacts genome evolution by driving substantial variation in transposon numbers between species.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis

    Anneli Cooper, Hamidou Ilboudo ... Annette MacLeod
    Common kidney disease risk variants in African populations are associated with reduced susceptibility to deadly African trypanosomes.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Gene Variation: The double-edged sword of evolution

    Etty Kruzel-Davila, Karl Skorecki
    Two gene variants provide different levels of protection against sleeping sickness, but this comes with an increased risk of developing chronic kidney disease.
    Version of Record
    Insight
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Simultaneous measurement of chromatin accessibility, DNA methylation, and nucleosome phasing in single cells

    Sebastian Pott
    A new method that measures multiple aspects of chromatin organization in single cells has a possible application to study regulatory processes in heterogeneous samples.
    1. Genetics and Genomics

    On the mechanistic nature of epistasis in a canonical cis-regulatory element

    Mato Lagator, Tiago Paixão ... Călin C Guet
    Thermodynamic framework accurately predicts the sign of epistasis and its environment dependence for a canonical cis-regulatory element.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Heredity: The gene family that cheats Mendel

    J Dylan Shropshire, Antonis Rokas
    Some alleles of the wtf gene family can increase their chances of spreading by using poisons to kill other alleles, and antidotes to save themselves.
    Version of Record
    Insight
    1. Genetics and Genomics

    A large gene family in fission yeast encodes spore killers that subvert Mendel’s law

    Wen Hu, Zhao-Di Jiang ... Li-Lin Du
    Two members of a large fission yeast (Schizosaccharomyces pombe) gene family are shown to act as spore killers that enhance their own transmission into progenies by impeding the maturation of spores not inheriting them.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    wtf genes are prolific dual poison-antidote meiotic drivers

    Nicole L Nuckolls, María Angélica Bravo Núñez ... Sarah E Zanders
    Selfish wtf meiotic drive genes use overlapping transcripts to encode both a trans-acting poison to kill gametes that do not inherit the gene and a gamete-autonomous antidote to specifically rescue the gametes that do.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    The dynamic three-dimensional organization of the diploid yeast genome

    Seungsoo Kim, Ivan Liachko ... Maitreya J Dunham
    Yeast homologous chromosomes exhibit condition-specific mitotic pairing at both global and local scales.