Aline Jelenkovic, Yoon-Mi Hur ... Karri Silventoinen
Genetic variance of adult human height shows a generally increasing trend across the birth-year cohorts but heritability estimates do not present any clear pattern of secular changes over a century.
Adria C LeBoeuf, Patrice Waridel ... Laurent Keller
The socially exchanged fluid passed mouth-to-mouth during trophallaxis contains molecules that can influence development, potentially mediating communal control of colony phenotypes.
Profiling of fibroblasts across mammals captures differences in longevity at the level of global gene expression and metabolite levels and reveals pathways that define these differences.
Joshua S Greene, May Dobosiewicz ... Cornelia I Bargmann
A quantitative trait locus that includes two pheromone receptor genes affects foraging behavior; for one of the genes, the two alleles of the QTL have opposite effects because of distinct sites of expression.
Yehudit Hasin-Brumshtein, Arshad H Khan ... Desmond J Smith
In depth characterization of gene expression in the mouse hypothalamus will facilitate understanding of the molecular pathways that affect metabolic traits and discovers new genes associated with these pathways.
Computational analysis of MNase-seq data reveals that alternatively positioned nucleosomes are prevalent in both yeast and human cells and create significant heterogeneity within cell populations.
Andrew T Timberlake, Jungmin Choi ... Richard P Lifton
Epistatic interactions of rare loss of function mutations in SMAD6 and a common variant modifier near BMP2 are the most common cause of midline craniosynostosis in humans.
Mutations affecting a nuclear encoded metalloprotease cause of a new form of mitochondriopathy, highlighting the importance of this protease for mitochondrial function in humans.
