Browse our latest Genetics and Genomics articles

Page 135 of 144
    1. Genetics and Genomics
    2. Plant Biology

    Contesting the presence of wheat in the British Isles 8,000 years ago by assessing ancient DNA authenticity from low-coverage data

    Clemens L Weiß, Michael Dannemann ... Hernán A Burbano
    A computational method to authenticate low-coverage ancient DNA experiments shows that putative wheat sequences from 8000 years old sediments are most likely not of ancient origin.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Genetic and epigenetic variation in the lineage specification of regulatory T cells

    Aaron Arvey, Joris van der Veeken ... Alexander Y Rudensky
    There is limited epigenetic conservation of lineage-specific DNA elements in Treg cells, and genetic variation in Treg cell specific enhancers is associated with autoimmune disease.
    1. Developmental Biology
    2. Genetics and Genomics

    Deployment of a retinal determination gene network drives directed cell migration in the sea urchin embryo

    Megan L Martik, David R McClay
    The gene regulatory network controlling directed cell migration in a sea urchin is strikingly similar to a sub-circuit for eye development in Drosophila, suggesting that ancient systems-level controls may be adapted for diverse functions in different animals.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Abundant toxin-related genes in the genomes of beneficial symbionts from deep-sea hydrothermal vent mussels

    Lizbeth Sayavedra, Manuel Kleiner ... Jillian M Petersen
    Beneficial symbiotic bacteria encode an exceptional number of toxin-related genes that are all expressed by the symbionts in the host, supporting their key role in host-microbe interactions.
    1. Cell Biology
    2. Genetics and Genomics

    KPNB1 mediates PER/CRY nuclear translocation and circadian clock function

    Yool Lee, A Reum Jang ... John B Hogenesch
    KPNB1 regulates rhythmic spatio-temporal nuclear import of the PER/CRY complex and is required for negative feedback repression in mammalian and fly clock function.
    1. Cell Biology
    2. Genetics and Genomics

    Selections that isolate recombinant mitochondrial genomes in animals

    Hansong Ma, Patrick H O'Farrell
    Recombinant mitochondrial genomes can be selected, traits can be genetically mapped and new genetic combinations can be made.
    1. Genetics and Genomics

    Wild worm embryogenesis harbors ubiquitous polygenic modifier variation

    Annalise B Paaby, Amelia G White ... Matthew V Rockman
    Cryptic alleles affecting embryonic development are widespread in wild C. elegans populations.
    1. Developmental Biology
    2. Genetics and Genomics

    Genome-wide errant targeting by Hairy

    Kurtulus Kok, Ahmet Ay ... David N Arnosti
    Pervasive ‘futile cycling’ by chromatin-modifying factors suggests a mechanism for creating new links in gene regulatory networks.
    1. Genetics and Genomics
    2. Plant Biology

    Stress induced gene expression drives transient DNA methylation changes at adjacent repetitive elements

    David Secco, Chuang Wang ... Ryan Lister
    Phosphate starvation in rice induces widespread, but transient, modulation of DNA methylation near stress responsive genes that is independent from the RNA-directed DNA methylation pathway.
    1. Ecology
    2. Genetics and Genomics

    Viral dark matter and virus–host interactions resolved from publicly available microbial genomes

    Simon Roux, Steven J Hallam ... Matthew B Sullivan
    From public microbial genomes, VirSorter revealed 12,498 viral genome sequences that expand the map of the global virosphere and whose analyses improve understanding of viral taxonomy, evolution and virus-host interactions.