Browse our latest Genetics and Genomics articles

Page 8 of 143
    1. Cell Biology
    2. Genetics and Genomics

    Cytosolic Carboxypeptidase 5 maintains mammalian ependymal multicilia to ensure proper homeostasis and functions of the brain

    Rubina Dad, Yujuan Wang ... Hui-Yuan Wu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    Becker muscular dystrophy mice showed site-specific decay of type IIa fibers with capillary change in skeletal muscle

    Daigo Miyazaki, Mitsuto Sato ... Akinori Nakamura
    BMD mice with three different in-frame deletions corresponded to the severity of BMD patients with the same deletions, and they showed type IIa muscle fibers reduction with morphological capillary changes.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    ZC3H11A mutations cause high myopia by triggering PI3K-AKT and NF-κB mediated signaling pathway in humans and mice

    Chong Chen, Qian Liu ... Xinting Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Evolutionary Biology
    2. Genetics and Genomics

    Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction

    James Boocock, Noah Alexander ... Leonid Kruglyak
    Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating efficiency.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Proteostasis modulates gene dosage evolution in antibiotic-resistant bacteria

    Chinmaya Jena, Saillesh Chinnaraj ... Nishad Matange
    Gene duplication in antibiotic-resistant bacteria mitigates elevated demand for expression, facilitating adaptation to antibiotics and alleviating costs of proteolytic instability of the drug target.
    1. Developmental Biology
    2. Genetics and Genomics

    Evaluating the transcriptional regulators of arterial gene expression via a catalogue of characterized arterial enhancers

    Svanhild Nornes, Susann Bruche ... Sarah De Val
    Identification and characterization of enhancers for eight key arterial genes reveal transcription factors associated with different aspects of endothelial gene expression specificity and provide a tool for a better understanding of arterial differentiation.
    1. Developmental Biology
    2. Genetics and Genomics

    Vascular Development: Enhancing our understanding of endothelial cells

    Guillermo Luxán
    What determines whether an endothelial cell becomes part of an artery, a vein or a capillary?
    Version of Record
    Insight
    1. Genetics and Genomics
    2. Evolutionary Biology

    The paradox of extremely fast evolution driven by genetic drift in multi-copy gene systems

    Xiaopei Wang, Yongsen Ruan ... Haijun Wen
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete
    1. Genetics and Genomics

    Maf-family bZIP transcription factor NRL interacts with RNA-binding proteins and R-loops in retinal photoreceptors

    Ximena Corso Diaz, Xulong Liang ... Anand Swaroop
    Tissue-specific transcription factors, such as basic motif leucine zipper protein NRL, interact with a plethora of RNA-binding proteins to perform pleiotropic functions during distinct steps of transcription process to generate quantitatively precise patterns of gene expression in neuronal cells.
    1. Genetics and Genomics
    2. Evolutionary Biology

    The Generalized Haldane (GH) model tracking population size changes and resolving paradoxes of genetic drift

    Yongsen Ruan, Xiaopei Wang ... Chung-I Wu
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Solid