Browse our latest Genetics and Genomics articles

Page 84 of 144
    1. Genetics and Genomics
    2. Neuroscience

    Investigation of Drosophila fruitless neurons that express Dpr/DIP cell adhesion molecules

    Savannah G Brovero, Julia C Fortier ... Michelle N Arbeitman
    Analyses of fru P1 neurons that express dpr/DIP genes reveal roles for subsets of neurons in courtship, and the roles of Dpr/DIPs and the sex hierarchy in neuroanatomical sexual dimorphism.
    1. Genetics and Genomics

    A confinable home-and-rescue gene drive for population modification

    Nikolay P Kandul, Junru Liu ... Omar S Akbari
    Generation of a home-and-rescue gene drive targeting an essential gene reveals confinable population modification.
    1. Evolutionary Biology
    2. Genetics and Genomics

    High-quality carnivoran genomes from roadkill samples enable comparative species delineation in aardwolf and bat-eared fox

    Rémi Allio, Marie-Ka Tilak ... Frédéric Delsuc
    High-quality genomes can be obtained from roadkill samples and used in population genomics for species delimitation with conservation implications.
    1. Genetics and Genomics

    Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzees

    Briana E Mittleman, Sebastian Pott ... Yoav Gilad
    A comparative analysis of human and chimpanzee polyadenylation site usage establishes alternative polyadenylation as another key mechanism underlying the genetic regulation of transcript and protein expression levels in primates.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Alzheimer’s Disease: Exploring the origins of nucleation

    Katarzyna Marta Zoltowska, Lucía Chávez-Gutiérrez
    An approach called deep mutational scanning is improving our understanding of amyloid beta aggregation.
    Version of Record
    Insight
    1. Evolutionary Biology
    2. Genetics and Genomics

    Evolutionary transcriptomics implicates HAND2 in the origins of implantation and regulation of gestation length

    Mirna Marinić, Katelyn Mika ... Vincent J Lynch
    The transcription factor HAND2 evolved uterine expression during the origins of pregnancy and may be important for maternal-fetal immune signaling and parturition.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    The genetic landscape for amyloid beta fibril nucleation accurately discriminates familial Alzheimer’s disease mutations

    Mireia Seuma, Andre J Faure ... Benedetta Bolognesi
    A massively parallel analysis of the effects of mutations on amyloid beta nucleation provide the first comprehensive atlas of how mutations alter the formation of amyloid fibrils.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Placenta: When the past informs our future

    Abigail LaBella
    Comparing the genes expressed at the maternal-fetal interface in different species helps to pinpoint those that contribute to a healthy pregnancy by regulating the activity of the immune system.
    Version of Record
    Insight
    1. Evolutionary Biology
    2. Genetics and Genomics

    Evolutionary dynamics of transposable elements in bdelloid rotifers

    Reuben W Nowell, Christopher G Wilson ... Timothy G Barraclough
    An investigation of transposable element evolution in a group of long-term asexual animals shows that many of the predicted effects of asexuality are not observed.
    1. Genetics and Genomics
    2. Neuroscience

    Mayday sustains trans-synaptic BMP signaling required for synaptic maintenance with age

    Jessica M Sidisky, Daniel Weaver ... Daniel Babcock
    Maintaining synaptic structure and function over time requires continuous signaling from pathways that are crucial for synapse development.