Browse our latest Genetics and Genomics articles

Characterisation of SARS-CoV-2 genomic divergence in healthcare-associated outbreaks demonstrates that the inclusion of healthcare workers in contact networks identifies additional links in SARS-CoV-2 transmission pathways.

DNA methylation data can be harnessed to provide insights into molecular and phenotypic differences associated with the spectrum of psychosis diagnoses.

A single protein catalyzes site-specific DNA recombination upon blue-light illumination.

SARS-CoV-2 can spread efficiently within care homes causing outbreaks among residents, who are at increased risk of severe disease, emphasising the importance of stringent infection control in this population.

Temporal changes in genome-wide enhancer transcription activity during a transdifferentiation event reveal additive and synergistic enhancer cooperation.

A mutant impaired for ribosome recycling exhibits translational reprogramming wherein strong mRNAs outcompete weak mRNAs, also observed when preinitiation complexes are diminished by eIF2α phosphorylation or 40S ribosomal subunit depletion.

In the context of susceptibility to severe COVID-19, the observations of a study provide the basis for a personalized interferon-based therapy in patients with rare TLR7 variants.

Evidence is mounting that rare loss-of-function variants in the TLR7 gene predispose men with no medical history to severe forms of COVID-19.

Global, multi-angled genetic analyses identified an age-associated loss of stem cell lineage fidelity that was linked to changes in polycomb regulation in the Drosophila intestinal epithelium.

Mid-gestational exposure to maternal immune activation drives a sequence of transcriptional signatures and developmental pathology in embryonic mouse cortex, culminating in altered lamination and cellular lineage specification.