Browse our latest Microbiology and Infectious Disease articles

The crystal structure of a PfRh family protein from a malaria parasite has been solved and shows that PfRh5-which the parasite uses to invade human red blood cells-has a novel protein fold.

An experimentally constrained model shows that Escherichia coli faces fitness trade-offs in chemotaxis behaviors, and that adaptation of phenotypic diversity through altered gene regulation permits populations to resolve these trade-offs.

Favipiravir, a novel nucleoside analogue, can clear a persistent norovirus infection in vivo through lethal mutagenesis.

The pattern of past Ebola outbreaks is indicative of an effective reproductive ratio of less than 1, which can lead to the generation of a range of outbreak sizes consistent with the scale of the ongoing epidemic.

Measuring HIV-1 DNA levels at the time of stopping antiretroviral therapy (when initiated during primary infection) predicts clinical progression and the time taken for plasma viraemia to become detectable.

Predicting the pandemic potential of influenza viruses from genetic sequence data could transform pandemic risk assessment but progress towards this goal will require the integration of experimental work, computational tools, and virus surveillance.

The anticonvulsant drug lamotrigine inhibits bacterial ribosome biogenesis and reveals an unexplored role for initiation factor 2 (IF2) in ribosome assembly.