A peroxidase-containing nanocompartment in the bacterial pathogen Mycobacterium tuberculosis protects against oxidative stress and antibiotic treatment in the host.
Healthcare workers working on COVID-19 wards experience a 31-fold increased risk of infection with SARS-CoV-2 compared to colleagues on non-COVID-19 wards whilst wearing fluid-resistant surgical masks, and FFP3 respirators provide up to 100% protection against infection.
Andreas Hober, Khue Hua Tran-Minh ... Fredrik Edfors
Immuno-affinity enrichment combined with liquid chromatography-mass spectrometry can be used to detect viral proteins to confirm the presence of SARS-CoV-2 in clinical samples.
The gut microbiota of East Asians is distinct, dissociated from body mass, and self-sustains compared to White subjects from the same region, and therein may underpin a key health disparity.
Marloes Grobben, Karlijn van der Straten ... Marit J van Gils
SARS-CoV-2 infection and vaccination elicit antibodies that cross-react with other human coronavirus spike proteins, indicating the spike S2 subdomain as a potential target strategy to develop a pan-coronavirus vaccine.
Very frequent viral kinetics in liver transplant patients reveals that the liver is not only the source of hepatitis C virus (HCV) production, but also plays a major role in extracellular HCV clearance.
Arielle Woznica, Ashwani Kumar ... Julie K Pfeiffer
Developing Monosiga brevicollis as a model to study choanoflagellate immune responses reveals that the innate immune protein STING mediates responses to cyclic dinucleotides in choanoflagellates, providing insight into the evolution of STING signaling on the animal stem lineage.
At most physiological concentrations, the short-chain fatty acids propionate and butyrate affect histone acetylation by modifying and activating the acetyltransferase p300/CBP, rather than by inhibiting histone deacetylases.
