Browse our latest Microbiology and Infectious Disease articles

Bioinformatics analyses and experiments in mouse models reveal how Escherichia coli accesses the molecular hydrogen pool to boost colonization during acute colitis.

HIV-1 capsids enter the host cell nucleus, where they are partially disrupted to release the viral genome upon completion of reverse transcription.

The presence of certain HLA alleles drives the emergence or maintenance of otherwise deleterious drug-resistant mutations in patients living with HIV, even when the patient is antiretroviral treatment naïve.

High-resolution imaging techniques reveal new insights into the actions of the retrovirus HIV-1 inside host cells.

A novel dimethylsulfoniopropionate lyase was identified, which catalyzes dimethyl sulfide releasing by a new mechanism and is found in several bacterial lineages, revealing its important roles in global sulfur cycling.

Type I IFN is a key determinant of pathogenic neutrophil activity and drives tissue pathology through modulation of IL-18 levels during genital HSV infection.

The aldehyde 4-hydroxy-2-nonenal is a novel component of the host antimicrobial reactive oxygen burst, and the bacterium Listeria monocytogenes encodes genes specifically for its detoxification.

Broader case variation in respiratory viral load, and in shedding virus via droplets and aerosols, for SARS-CoV-2 than influenza A(H1N1)pdm09 facilitates greater transmission heterogeneity in the COVID-19 pandemic than the 2009 flu pandemic.

Cell culture adaptation of SARS-CoV-2 is prevented on human airway cells with an active serine protease-mediated entry pathway, allowing the production of genetically stable virus stocks for laboratory experiments.

M. tuberculosis, the bacterium that causes the disease tuberculosis, uses a signaling system that senses multiple products of the host's immune system to modify gene expression to colonize the lung.