Browse our latest Neuroscience articles

Page 343 of 599
    1. Neuroscience

    Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease

    David Moreno-Delgado, Mar Puigdellívol ... Peter J McCormick
    Progression of Huntington's disease can be slowed by altering dopamine signalling through the Dopamine 1 receptor - Histamine 3 receptor heteromer.
    1. Neuroscience

    Whole-brain mapping of socially isolated zebrafish reveals that lonely fish are not loners

    Hande Tunbak, Mireya Vazquez-Prada ... Elena Dreosti
    Social isolation increases anti-social behaviour by altering activity in brain areas related to anxiety, stress, and reward.
    1. Neuroscience

    Acute disruption of the synaptic vesicle membrane protein synaptotagmin 1 using knockoff in mouse hippocampal neurons

    Jason D Vevea, Edwin R Chapman
    Knockoff is a tool for researchers who wish to acutely disrupt a membrane protein.
    1. Neuroscience

    Hippocampal remapping as hidden state inference

    Honi Sanders, Matthew A Wilson, Samuel J Gershman
    Context representation in the hippocampus incorporates uncertainty and requires inference based on past experience.
    1. Neuroscience

    Memory: How the brain constructs dreams

    Erin J Wamsley
    Deep inside the temporal lobe of the brain, the hippocampus has a central role in our ability to remember, imagine and dream.
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    Insight
    1. Neuroscience

    Dreaming with hippocampal damage

    Goffredina Spanò, Gloria Pizzamiglio ... Eleanor A Maguire
    A provoked awakening protocol during sleep reveals that selective bilateral hippocampal damage in humans is associated with reduced frequency, quality, and content of dreaming.
    1. Neuroscience

    Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

    Laura Sebastian Monasor, Stephan A Müller ... Sabina Tahirovic
    APPPS1 microglia express disease-associated proteomic signatures of Alzheimer's disease earlier, compared to the APP-KI, and these differences correlate with the levels of fibrillar Aβ and impaired microglial phagocytic function.
    1. Neuroscience

    Differences in reward biased spatial representations in the lateral septum and hippocampus

    Hannah S Wirtshafter, Matthew A Wilson
    Reward-related spatial information is preferentially represented in the lateral septum compared to the hippocampus and may be used downstream to direct the animal to rewarded locations.
    1. Neuroscience

    A big-data approach to understanding metabolic rate and response to obesity in laboratory mice

    June K Corrigan, Deepti Ramachandran ... Alexander S Banks
    The metabolic rate of mice is disproportionately affected by the site of experimentation, affecting the phenotypic interpretation of genetically modified strains.
    1. Neuroscience

    High-fat diet enhances starvation-induced hyperactivity via sensitizing hunger-sensing neurons in Drosophila

    Rui Huang, Tingting Song ... Liming Wang
    Fruit flies fed with high-fats diets are hyper-sensitive to a hunger hormone AKH and exhibit enhanced food-seeking behavior when starved.