A disinhibitory motif in the retina mediates noise resilience of motion detection using an inverted algorithm of disinhibition due to the interplay between network activity and synaptic plasticity.
Percy Griffin, Patrick W Sheehan ... Erik S Musiek
The BMAL1-REV-ERB axis controls expression of complement C4b expression and microglial synaptic phagoctyosis, providing a link between cellular circadian clock function and synaptic regulation.
Anton Fomenko, Kai-Hsiang Stanley Chen ... Robert Chen
Transcranial low-intensity ultrasound applied in block design and at low duty cycles and longer sonication durations can safely and non-invasively suppress human motor-evoked potentials, possibly via GABA-A-mediated inhibitory pathways.
Hillary A Miller, Elizabeth S Dean ... Scott F Leiser
Modulation of the aging process through cell signaling represents a recent and exciting area of study with the potential for development of therapeutics to extend human health.
Mice exposed to complex early adversity show similar diffusion MRI changes to those reported in humans and sex-specific changes in connectivity that differentially affect contextual deficits in males and females.
Sam Vickery, William D Hopkins ... Felix Hoffstaedter
Openly available structural imaging processing pipeline for chimpanzees including registration templates and macro-anatomical parcellation shows human-like cerebral aging and medial hemispheric organization.
Yulia Bereshpolova, Xiaojuan Hei ... Harvey A Swadlow
In the visual system, three rules guide the thalamocortical connectivity of cortical fast-spike interneurons and are key to understand the potent and broadly tuned feed-forward inhibition that they generate.
Thomas Zhihao Luo, Adrian Gopnik Bondy ... Carlos D Brody
Techniques are presented to facilitate widespread and standardized chronic use of Neuropixels probes for high-yield, long-term neural recording in freely moving animals.
