The new drug 3,6’-dithiopomalidomide mitigates key markers of neuronal death and neuroinflammation and improves acute behavioral outcome measures in traumatic brain injury, a common, debilitating disorder that lacks effective treatment.
Anthony H Tsang, Christiane E Koch ... Henrik Oster
Adiponectin signaling integrates metabolic state information to regulate circadian clock function in hypothalamic appetite regulating centers, food intake rhythms, and body weight.
Gabriel L McKinsey, Carlos O Lizama ... Thomas D Arnold
P2ry12-CreER robustly and specifically labels microglia in fate-mapping and ribosomal profiling experiments, revealing new markers for myeloid subpopulations in the central nervous system.
Walter R Mancia Leon, Julien Spatazza ... Arturo Alvarez-Buylla
Pcdhg determine survival of the GABAergic cortical interneuron population that is necessary to establish and maintain proper excitatory to inhibitory balance in the cerebral cortex.
Maria Luisa Saggio, Dakota Crisp ... William C Stacey
Taxonomy of seizure dynamics (TSD) provides a rigorous method for classifying and quantifying seizures and a principled framework for understanding seizure initiation and propagation.
Chiara La Rosa, Francesca Cavallo ... Luca Bonfanti
The higher amount of cortical immature neurons in brains with expanded neocortices may represent a reservoir of young cells for mammals with reduced neurogenesis.
Santosh Chandrasekaran, Ameya C Nanivadekar ... Lee E Fisher
Cervical spinal cord stimulation evokes sensory percepts in the missing hand and arm of people with upper-limb amputation, regardless of amputation level or time post-amputation.