Jonathan Zirin, Barbara Jusiak ... Norbert Perrimon
A CRISPR knock-in approach enables the efficient generation of tissue-specific LexA and QF driver lines which can simultaneously control gene expression in multiple tissues.
Jacques Pesnot Lerousseau, Christopher Summerfield
Spatial mapping serves as a cognitive scaffold for acquiring abstract conceptual invariances across sensory domains, shedding light on the mechanisms of human learning.
Multifaceted properties of the water-soluble derivative of antibiotic heliomycin enable it to offer greater antitumor value than its parent compound by inhibiting the tNOX-NAD+-SIRT1 axis to induce apoptosis.
Domingos Leite de Castro, Miguel Aroso ... Paulo Aguiar
Adaptive delayed feedback control is presented as a new real-time, closed-loop control algorithm for neurostimulation which can disrupt oscillations and reduce network synchrony in neuronal populations.
Kyounghee Min, Batuhan Yenilmez ... Michael P Czech
Stellate cell lactate transporter MCT1 significantly contributes to liver fibrosis through increased collagen 1 protein expression in vitro and in vivo.
Laure Mignerot, Clotilde Gimond ... Christian Braendle
Caenorhabditis elegans egg-laying behaviour shows pronounced variation in natural populations, making it a promising model to investigate the microevolution of a simple neural circuit.