Posttranslational modifications of tubulins regulate axonal growth and regeneration by controlling the stabilities of microtubules or modulating their interactions with microtubule-associated proteins.
A biochemical approach shows co-phase separation of CCL5 with heparan sulfate establishes a specific chemokine concentration gradient for chemotactic activity.
Thomas Morgan Li, Victoria Zyulina ... Theresa T Lu
Interferon contributes to photosensitivity at least in part by causing Langerhans cell ADAM17 dysfunction, raising the possibility that anifrolumab ameliorates lupus skin disease in part by restoring Langerhans cell function.
Carlos Gonzalez-Islas, Zahraa Sabra ... Peter Wenner
Chronic perturbations of spiking activity trigger compensatory changes in GABAergic synaptic strength, but not compensatory changes in AMPAergic synaptic strength.
Etienne Combrisson, Ruggero Basanisi ... Andrea Brovelli
Reward and punishment learning is represented in partly overlapping regions of the brain while relying on specific intra- and inter-regional interactions.