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An epigenomic analysis in mouse macrophages reveals that a highly abundant transposable element exhibits activity as an immune inducible regulatory element.

Chronic stimulation with odors at naturally occurring concentrations only mildly impacts early stages of olfactory processing, suggesting a need to re-interpret prevailing models of how chronic odor exposure affects olfactory function.

A randomized placebo-controlled trial with behavioral, neuroimaging, and physiological measures reveals that oxytocin treatment facilitates pleasure and brain reward responses only to gentle stroking social touch by increasing peripheral blood concentrations.

Oxygen levels at the time of T cell activation are major determinants of function, even when T cells are subsequently expanded in high levels of oxygen.

MLL1-mediated H3K4 methylation is directly enhanced by cis-tail H3 acetylation, as shown through both in vitro and in vivo experiments.

Structural biology studies reveal the importance of protein dynamics on understanding molecular mechanisms underlying allosteric modulation of G protein-coupled receptors (GPCR) that offer insights into future GPCR research and drug discovery.

Genetically fusing weakly homodimerizing proteins to the C-terminus of IgG antibodies to induce reversible catenation on a target surface greatly enhances antigen-binding avidity, offering a promising approach for a range of antibody applications.