Browse our latest research

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    1. Cancer Biology
    2. Medicine

    Long COVID in cancer patients: preponderance of symptoms in majority of patients over long time period

    Hiba Dagher, Anne-Marie Chaftari ... Issam I Raad
    Long COVID occurred in the majority of cancer patients diagnosed with acute COVID-19 with a preponderance of symptoms (such as fatigue, sleep disturbances, and gastrointestinal symptoms) over a long time period.
    1. Structural Biology and Molecular Biophysics

    Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster

    Ahmed-Noor A Agip, Injae Chung ... Judy Hirst
    Structures of respiratory complex I from the insect and metazoan model system Drosophila melanogaster reveal its close relationships with the mammalian complex and provide a foundation for new approaches to disentangle mechanisms of complex I catalysis and regulation.
    1. Cell Biology
    2. Developmental Biology

    Control of craniofacial development by the collagen receptor, discoidin domain receptor 2

    Fatma F Mohamed, Chunxi Ge ... Renny T Franceschi
    Discoidin domain receptor 2 controls craniofacial morphology by acting in skeletal progenitor cells and chondrocytes to control collagen matrix organization, chondrocyte polarity, and growth.
    1. Neuroscience

    Multimodal mapping of cell types and projections in the central nucleus of the amygdala

    Yuhan Wang, Sabine Krabbe ... Scott M Sternson
    In the central amygdala, transcriptomic definition of cell types and corresponding spatial transcriptomic analysis reveals major regional differences in molecular organization and relates newly identified molecularly defined cell types to major axon projection targets.
    1. Neuroscience

    Gasotransmitter modulation of hypoglossal motoneuron activity

    Brigitte M Browe, Ying-Jie Peng ... Alfredo J Garcia III
    Electrophysiological analyses reveal interactions between gasotransmitter enzymes and their respective products that regulate hypoglossal motoneuron excitability and may drive changes in upper airway tone in obstructive sleep apnea and perturb behaviors such as vocalization and swallowing.
    1. Microbiology and Infectious Disease

    Human influenza virus infection elicits distinct patterns of monocyte and dendritic cell mobilization in blood and the nasopharynx

    Sindhu Vangeti, Sara Falck-Jones ... Anna Smed-Sörensen
    Patterns of monocyte and dendritic cell mobilization and function during human respiratory viral infections are tissue-specific and pathogen-specific, and future studies must perform comparative investigations in blood and the site of infection for a comprehensive assessment of immune responses.
    1. Ecology
    2. Evolutionary Biology

    Community diversity is associated with intra-species genetic diversity and gene loss in the human gut microbiome

    Naïma Madi, Daisy Chen ... Nandita R Garud
    Longstanding eco-evolutionary theories are tested using shotgun metagenomic data from the human gut microbiome, showing links between community diversity and the evolutionary trajectory of a focal species within the community.
    1. Developmental Biology
    2. Plant Biology

    The circadian clock controls temporal and spatial patterns of floral development in sunflower

    Carine M Marshall, Veronica L Thompson ... Stacey L Harmer
    The circadian clock acts with light response pathways to tightly synchronize daily rhythms in maturation of hundreds of florets in sunflower, promoting timely visits by pollinators and creating ring-like patterns on developing heads.
    1. Immunology and Inflammation

    Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2

    Oksana Tsyklauri, Tereza Chadimova ... Ondrej Stepanek
    Regulatory T cell suppress cytotoxic T cells in autoimmunity and cancer by taking up IL-2.
    1. Neuroscience

    Sensory input-dependent gain modulation of the optokinetic nystagmus by mid-infrared stimulation in pigeons

    Tong Xiao, Kaijie Wu ... Yan Yang
    Simultaneous stimulation and recording in awake-behaving pigeons showed that mid-infrared stimulation, as a promising neuromodulation approach, could facilitate or suppress neuronal firing activity depending on its ongoing sensory responsiveness levels, and cause reversible and gain modulation on sensorimotor behavior.