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Volume-EM reconstruction of a whole-body desmosomal connectome including all muscles and their desmosomal partners in a Platynereis larva provides a detailed view of the organisation of the entire locomotor system in an animal.

Genome sequence analysis of Mycobacterium tuberculosis clinical isolates and subsequent validation in laboratory and animal infection models identify previously unrecognized genetic mutations in DNA repair genes that contribute to the development of drug resistance.

Genetic analyses using a new oral infection mouse model demonstrate that cell death pathways protect against the gastrointestinal bacterial pathogen Shigella flexneri.

Neocortical activity is drastically different around awake than sleep hippocampal ripples.

A pathway of unconventional secretion for alpha-synuclein, a protein which may spread in the brain as part of the pathology of Parkinson’s disease.

PIP₂ inhibits the proton-activated chloride (PAC) channel by selectively stabilizing its desensitized state.

Neurexins are presynaptic adhesion molecules in the serotonin system which regulate neuron survival and serotonin neuromodulation through active zone formation and serotonin release.

Lysine-specific demethylase-1 acts as an epigenetic barrier against glucocorticoid-induced atrophy and exercise-induced hypertrophy in skeletal muscle.

Blocking an atrophic 'master regulator' pathway following tendon tear does not affect resulting skeletal muscle atrophy.

Myostatin signaling governs neonatal longitudinal muscle growth and neuromuscular contractures in a sex-dependent manner, identifying a potential avenue for contracture treatment and underscoring the need to consider sex as a biological variable in the pathophysiology of acquired neuromuscular disorders.