In juvenile songbirds, neural sequences pre-exist tutor exposure, and the process of learning a new song may make use of existing neural sequences as a stable substrate for new behavioral changes.
Genetically fusing weakly homodimerizing proteins to the C-terminus of IgG antibodies to induce reversible catenation on a target surface greatly enhances antigen-binding avidity, offering a promising approach for a range of antibody applications.
A screen of lactic acid bacteria reveals that diet modulates the age-dependent decline of thermotaxis behavior in C. elegans without changing the organismal lifespan.
Structural biology studies reveal the importance of protein dynamics on understanding molecular mechanisms underlying allosteric modulation of G protein-coupled receptors (GPCR) that offer insights into future GPCR research and drug discovery.
Affectionate touch in everyday life is linked to lower self-reported burden and is associated with higher endogenous oxytocin levels during times of prolonged stress.
A novel immunoassay for ApoB-100, the main protein component of lipoproteins, enables the development of methods to enrich extracellular vesicles from human plasma while depleting both lipoproteins and free proteins.
Plasmodium falciparum apicoplast SufS is required for both iron-sulfur synthesis and tRNA modification by MnmA, a novel paradigm that is likely to apply to other plastid-containing organisms.
Sindhu Mohandas, Prasanna Jagannathan ... RECOVER Mechanistic Pathways Task Force
Immune dysregulation is thought to be a hallmark of long COVID or PASC but there is a need for understanding the underlying mechanisms which drive the disease progression.
