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Page 528 of 1,765
    1. Epidemiology and Global Health

    Long term intrinsic cycling in human life course antibody responses to influenza A(H3N2): an observational and modeling study

    Bingyi Yang, Bernardo García-Carreras ... Derek A Cummings
    Cross-sectional serological data and mathematical models suggest the existence of long-term periodicity in human antibody responses arising from multiple exposures to influenza A(H3N2), providing insights into the interactions between exposure histories and future risks of infections.
    1. Ecology
    2. Evolutionary Biology

    Desiccation resistance differences in Drosophila species can be largely explained by variations in cuticular hydrocarbons

    Zinan Wang, Joseph P Receveur ... Henry Chung
    Evolutionary changes in cuticular hydrocarbons, a lipid layer on the insect epicuticle, underlie the evolution of desiccation resistance in Drosophila species.
    1. Genetics and Genomics

    Comprehensive re-analysis of hairpin small RNAs in fungi reveals loci with conserved links

    Nathan R Johnson, Luis F Larrondo ... Elena A Vidal
    A critical assessment of published microRNA/microRNA-like provides clues on features and conservation of these hairpin RNAs in fungi in addition to a centralized loci annotation resource for the community.
    1. Neuroscience

    Clarifying the role of an unavailable distractor in human multiattribute choice

    Yinan Cao, Konstantinos Tsetsos
    A previously reported positive influence of a distractor alternative on decision accuracy was driven by an unintended covariation between key variables, beyond which the distractor has a modest negative influence on accuracy, possibly mirroring asymmetric multiattribute context effects.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Clonal transcriptomics identifies mechanisms of chemoresistance and empowers rational design of combination therapies

    Sophia A Wild, Ian G Cannell ... Kirsty Sawicka
    Lineage resolved single-cell RNA-seq of mammary carcinoma models uncovers a metabolic vulnerability of taxane-resistant clones.
    1. Ecology

    Tree species and genetic diversity increase productivity via functional diversity and trophic feedbacks

    Ting Tang, Naili Zhang ... Xiaojuan Liu
    Species and genetic diversity promote tree community productivity by increasing functional diversity and reducing herbivore damage and soil fungal diversity.
    1. Physics of Living Systems

    The importance of intermediate filaments in the shape maintenance of myoblast model tissues

    Irène Nagle, Florence Delort ... Myriam Reffay
    Specific to muscles and essential for their development, desmin is revealed to be fundamental to the mechanics and shape maintenance of model muscle tissue even in early differentiating and unorganized systems through an integrated magnetic tensiometer approach.
    1. Computational and Systems Biology
    2. Neuroscience

    Normative decision rules in changing environments

    Nicholas W Barendregt, Joshua I Gold ... Zachary P Kilpatrick
    In environments that fluctuate over the course of deliberation, optimal decision strategies display novel dynamics that can explain human response behaviors better than commonly used alternatives.
    1. Developmental Biology
    2. Immunology and Inflammation

    Thymic macrophages consist of two populations with distinct localization and origin

    Tyng-An Zhou, Hsuan-Po Hsu ... Ivan L Dzhagalov
    Thymic macrophages are unique phagocytes with antigen-presenting abilities that comprise a Timd4+ subset of embryonic origin located in the cortex and a Cx3cr1+ subset derived from adult hematopoietic stem cells residing in the medulla.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Bidirectional promoter activity from expression cassettes can drive off-target repression of neighboring gene translation

    Emily Nicole Powers, Charlene Chan ... Gloria Ann Brar
    Bidirectional promoter activity, which is inherent to the promoters of selection cassettes used for genome editing, causes divergent transcription that can disrupt expression of genes neighboring cassette insertion sites, causing potent off-target effects.