Amanda M Hughes, Eleanor Sanderson ... Neil M Davies
It is unclear how much a child's BMI at age 8 affects their depressive and ADHD symptoms after family-level factors are accounted for, but a substantial impact on anxiety symptoms is unlikely.
Steffen M Recktenwald, Greta Simionato ... Stephan Quint
For severe COVID-19 patients' red blood cells, healthy donor plasma reduces pathological red blood cell shape alterations and improves microcapillary flow in vitro through an interaction between red blood cells and plasma.
Dan Zhang, Roxane P Spiegelhalder ... Michael T Raissig
The formation of stomatal 'helper cells' (=subsidiary cells) in grasses requires two opposing polarity domains with diverse roles in establishing division asymmetry.
Richard F Oppong, Antonio Terracciano ... Jun Ding
Two genome sequencing studies show a consistent association between blood mitochondrial DNA copy number (mtDNAcn) and personality traits and provide support for the hypothesis that mtDNAcn may be a biomarker that connects certain personality characteristics with mortality.
Genetic and biochemical analyses reveal that the bacterial nucleases PNPase and RNase R work in concert with a type III-A CRISPR-Cas immune system to process small CRISPR RNAs and ensure robust immunity against foreign nucleic acid invaders.
Scratch-AID, a deep learning-based system for automatic quantification of mouse scratching behavior, could replace labor-intensive manual quantification and facilitate high through-put anti-itch drug screening.
The impact of phosphorylation on the dynamics of RAS is considered to find allosteric binding sites on the flat surface of the protein, to which small molecules could bind and perturb the RAS-RAF interaction interface.
Two-photon Ca2+ imaging and computational modeling reveal major developmental trajectories of spontaneous activity in developing CA1 and identify important roles of network bi-stability and synaptic input characteristics for hippocampal burstiness before eye opening.
