Susanna Lemmelä, Eleanor M Wigmore ... Athena Matakidou
Elevated growth differentiation factor-15 (GDF15) levels do not appear to be a causal factor in body mass index (BMI) in humans but higher BMI does cause increases in GDF15.
Sobhika Agarwala, Keun-Young Kim ... Owen J Tamplin
Multiple imaging modalities resolved the ultrastructure of single hematopoietic stem cells in their endogenous niche, allowing identification of dopamine beta-hydroxylase positive cells as a functional niche cell type.
Laura R Edmondson, Alejandro Jiménez Rodríguez, Hannes P Saal
A simple efficient coding model predicts complex trade-offs in resource allocation for sensory inputs with heterogeneous receptor densities and activation levels.
Th2 cell heterogeneity was revealed by combined transcriptome and T-cell receptor sequencing of single Th2 cells from lung and lymph node of helminth-infected mice and led to identification of a helminth-specific T-cell receptor.
Matthew A Dixon, Peter Winskill ... María-Gloria Basáñez
Marked geographical heterogeneity in global Taenia solium transmission rates indicate the need for setting-specific intervention strategies to achieve the WHO NTD 2021-2030 roadmap milestones for T. solium.
Visualizations, simulations, and examples are used to provide an accessible synthesis of the reasoning and assumptions behind commonly used causal discovery approaches.