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The phagocytic receptor CED-1 is kept at the appropriate level by E3 ligase trim-21-mediated ubiquitination-proteasomal degradation for apoptotic cell clearance, which is independent of retromer-dependent recycling and lysosomal degradation.

A phase shift between local contractions drives 3D cell motility in experiments and in model or how a finite area in the dipole-quadrupole space explains cell motion with zero total force.

Loss of nonstationary connectivity in a subcortical fronto-temporoparietal network distinguishes patients with minimal conscious state and unresponsive wakefulness state, strongly supporting the mesocircuit hypothesis.

The IgG4 subclass, previously considered anti-inflammatory due to its weak effector function, could either reduce or exacerbate autoantibody pathogenicity in the context of different IgG4-mediated autoimmune diseases.

Increased root exudation rate under combined drought and bacterial inoculation and bacterial growth stimulation by specific exudation metabolites support the idea of root recruitment of beneficial bacteria, especially under water stress.

HaloTag becomes resistant to lysosomal proteolysis upon ligand binding, enabling us to measure various types of autophagic flux easily and precisely by using HaloTag-containing reporters for processing assays.

The speed of replisomes in Escherichia coli depends on temperature and varies along the genome in a wave-like manner, with implications for bacterial physiology.

Human brain suggests an asymmetric organization along a functional cortical axis describing a hierarchical functional trajectory from perceptual/action to abstract cognition, which is heritable and comparable with macaque brain, suggesting (phylo)genetic conservation and adaptation.

Activation of Tacr1-expressing neurons including ON cells in the rostral ventromedial medulla inhibits acute and chronic itch-related behavior.

Fruit consumption of Jeholornis was evidenced and indicates seed dispersal was present from early in avian radiation.