Browse our latest research

Page 597 of 1,755
    1. Neuroscience

    Spatially bivariate EEG-neurofeedback can manipulate interhemispheric inhibition

    Masaaki Hayashi, Kohei Okuyama ... Junichi Ushiba
    Interhemispheric inhibition can be manipulated by directly and bidirectionally modulating the bilateral sensorimotor excitabilities in a spatially bivariate Brain-Computer Interface-based neurofeedback paradigm.
    1. Neuroscience

    Selfee, self-supervised features extraction of animal behaviors

    Yinjun Jia, Shuaishuai Li ... Wei Zhang
    Selfee, a self-supervised learning approach, is designed to extract comprehensive and discriminative features directly from raw videos of animal behaviors which can be used for in-depth analysis.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Obligate sexual reproduction of a homothallic fungus closely related to the Cryptococcus pathogenic species complex

    Andrew Ryan Passer, Shelly Applen Clancey ... Marco A Coelho
    A novel form of self-fertility evolved in Cryptococcus depauperatus, a close relative to the human pathogenic Cryptococcus species, in which sexual development is attained by self-signaling of a cognate pheromone and pheromone-receptor pair.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Key features of the genetic architecture and evolution of host-microbe interactions revealed by high-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice

    Shauni Doms, Hanna Fokt ... John F Baines
    Genetic variation influencing the gut microbiome is abundant among incipient mammalian host species, and cospeciating bacterial taxa display a unique genetic architecture.
    1. Cell Biology

    Ndc1 drives nuclear pore complex assembly independent of membrane biogenesis to promote nuclear formation and growth

    Michael Sean Mauro, Gunta Celma ... Shirin Bahmanyar
    Discovery of how cells couple addition of membranes with insertion of nuclear pore complexes to form and grow the nucleus.
    1. Biochemistry and Chemical Biology

    Cryo-EM structures reveal that RFC recognizes both the 3′- and 5′-DNA ends to load PCNA onto gaps for DNA repair

    Fengwei Zheng, Roxana Georgescu ... Michael E O'Donnell
    Cryo-EM shows a 5’ DNA site on the RFC clamp loader, in addition to the 3’ site, and biochemical study shows the 5’ site facilitates PCNA loading onto gaps, consistent with genetics indicating the 5’ DNA site facilitates gap repair.
    1. Structural Biology and Molecular Biophysics

    A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA

    Xingchen Liu, Christl Gaubitz ... Brian A Kelch
    Structural, biochemical, and cellular data reveal the mechanism by which the clamp loader attaches sliding clamps at gapped and nicked DNA to support DNA damage repair.
    1. Neuroscience

    Taste quality and hunger interactions in a feeding sensorimotor circuit

    Philip K Shiu, Gabriella R Sterne ... Kristin Scott
    Gustatory information and hunger state impinge on a local, multilayered circuit that drives feeding initiation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The spatiotemporal patterns of major human admixture events during the European Holocene

    Manjusha Chintalapati, Nick Patterson, Priya Moorjani
    Development of a genomic dating method that leverages ancestry covariance patterns in a single diploid individual reveals the timing of major admixture events during the European Holocene.
    1. Physics of Living Systems

    Hydrodynamic model of fish orientation in a channel flow

    Maurizio Porfiri, Peng Zhang, Sean D Peterson
    A hydrodynamic model of fish swimming in a channel predicts a critical flow speed for fish to successfully swim against a flow, unveiling a passive mechanism for rheotaxis to emerge without access to any sensory information.