Interhemispheric inhibition can be manipulated by directly and bidirectionally modulating the bilateral sensorimotor excitabilities in a spatially bivariate Brain-Computer Interface-based neurofeedback paradigm.
Selfee, a self-supervised learning approach, is designed to extract comprehensive and discriminative features directly from raw videos of animal behaviors which can be used for in-depth analysis.
Andrew Ryan Passer, Shelly Applen Clancey ... Marco A Coelho
A novel form of self-fertility evolved in Cryptococcus depauperatus, a close relative to the human pathogenic Cryptococcus species, in which sexual development is attained by self-signaling of a cognate pheromone and pheromone-receptor pair.
Genetic variation influencing the gut microbiome is abundant among incipient mammalian host species, and cospeciating bacterial taxa display a unique genetic architecture.
Fengwei Zheng, Roxana Georgescu ... Michael E O'Donnell
Cryo-EM shows a 5’ DNA site on the RFC clamp loader, in addition to the 3’ site, and biochemical study shows the 5’ site facilitates PCNA loading onto gaps, consistent with genetics indicating the 5’ DNA site facilitates gap repair.
Structural, biochemical, and cellular data reveal the mechanism by which the clamp loader attaches sliding clamps at gapped and nicked DNA to support DNA damage repair.
Manjusha Chintalapati, Nick Patterson, Priya Moorjani
Development of a genomic dating method that leverages ancestry covariance patterns in a single diploid individual reveals the timing of major admixture events during the European Holocene.
A hydrodynamic model of fish swimming in a channel predicts a critical flow speed for fish to successfully swim against a flow, unveiling a passive mechanism for rheotaxis to emerge without access to any sensory information.