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Combining particle tracking in living cells with statistical analysis demonstrates how the oligomeric organization of cell surface receptor influences their function, a necessary step in the development of drugs targeting specific receptor conformation.

Novel procedures for viral gene transfer in zebrafish enable visualization and manipulation of specific neurons.

Fibronectin can shift from a globular to fibrillated form when adsorbing to implant surfaces, and this shift makes it accessible to attachment by Staphylococcus epidermidis, which is the leading cause of implant-associated infections.

Hearing a single auditory error while speaking causes an adaptive change that corrects for that error the next time we say a word, providing empirical support for current models of speech sensorimotor adaptation and aligning speech with other motor domains.

Pathogenic mutations in KIF22, which dominantly cause bone dysplasia, improperly activate the motor during anaphase in dividing cells leading to chromosome recongression.

A biophysical model of the process by which bacteria transition from the motile planktonic state to the immobilized biofilm state yields testable predictions in terms of two dimensionless parameters, one describing nutrient availability and the other describing cellular dispersal.

The membrane nonlinearities of the dendritic arbor of striatal cholinergic interneurons conspire with the spatial distribution of its excitatory inputs to preferentially boost thalamic inputs.

An electrophysiology-based genetic screen in Drosophila identified a role for the E3 ligase Thin in presynaptic homeostatic plasticity.

A combination of single-molecule and in vivo FRET showed how drugs affect conformation of mGluR2 at different domains.

In response to proteotoxic stress, squamous cell carcinoma cells hijack the integrated stress response to promote recovery by bolstering protection of microtubule dynamics.