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Altered coupling of different brain waves during sleep is associated with worse brain features related to Alzheimer’s disease processes and cognitive performance, suggesting that sleep brain waves coupling may contribute to poorer brain and cognitive trajectories in ageing.

An amino acid dimorphism in HLA-C with an established impact on natural killer cell receptors plays an unexpected and significant role in T cell receptor recognition of HLA-C with relevance for tumor immunity.

METTL18 methylates histidine 245 of ribosomal protein RPL3, retards ribosome traversal at tyrosine codons, and thus ensures nascent protein folding for proteostasis maintenance.

New morphological data of a primitive placoderm fish demonstrate both high regionalization of squamation and the bipartite histological structure of scale are plesiomorphic for jawed vertebrates.

A new ethologically relevant model for investigating the neurobiology of solitary, asocial behavior in the blind mole rat.

A modified viral strategy reveals that ventral tegmental area dopamine cells receive substantial inputs from local sources, including distributed GABAergic and serotonergic inputs from the midbrain as well as extensive inputs from other midbrain dopamine cells.

When conducting fear conditioning in mice, cue-elicited activity bursts are primarily a result of nonassociative processes, and freezing behavior remains the best index for associative learning.

SoxB genes are sequentially expressed in cnidarian neurogenesis.

The reduction of bicarbonate secretion into the airways reproduces cystic fibrosis-like features, independently of chloride secretion.

Phenotypic variants that avoid antibiotic accumulation within clonal bacterial populations are a significant contributor to antibiotic treatment failure and can rely on previously unrecognised survival strategies such as fast growth during drug treatment.