Browse our latest research

Page 705 of 1,748
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis

    Virender Kumar Pal, Ragini Agrawal ... Amit Singh
    A gaseous signaling molecule hydrogen sulfide stimulates mitochondrial bioenergetics, maintains glutathione redox poise, and suppresses ROS to subvert viral rebound in latently infected CD4+ T cells from HIV subjects.
    1. Evolutionary Biology

    Evolutionary transcriptomics implicates new genes and pathways in human pregnancy and adverse pregnancy outcomes

    Katelyn Mika, Mirna Marinić ... Vincent J Lynch
    Comparative studies of gene expression in the uterus during pregnancy identifies new genes important for pregnancy and associated with complications such as preterm birth.
    1. Neuroscience

    A neural circuit for flexible control of persistent behavioral states

    Ni Ji, Gurrein K Madan ... Steven W Flavell
    Circuit-wide calcium imaging during C. elegans foraging elucidates the functional architecture of a neural circuit controlling the choice between two alternative behavioral states.
    1. Neuroscience

    Effects of arousal and movement on secondary somatosensory and visual thalamus

    Gordon H Petty, Amanda K Kinnischtzke ... Randy M Bruno
    Secondary somatosensory and visual thalamus monitor behavioral state, rather than movement, and may exist to alter cortical activity accordingly.
    1. Neuroscience

    CA1 pyramidal cell diversity is rooted in the time of neurogenesis

    Davide Cavalieri, Alexandra Angelova ... Rosa Cossart
    Embryonic birthdate is a crucial determinant of heterogeneity among CA1 principal neurons, which include a previously overlooked subpopulation of pioneer neurons.
    1. Neuroscience

    A functional topography within the cholinergic basal forebrain for encoding sensory cues and behavioral reinforcement outcomes

    Blaise Robert, Eyal Y Kimchi ... Daniel B Polley
    Activity levels in anterior and posterior cholinergic basal forebrain neurons are associated with distinct aspects of global brain state, sensory salience, reward expectation, and aversive reinforcement learning.
    1. Neuroscience

    Control of parallel hippocampal output pathways by amygdalar long-range inhibition

    Rawan AlSubaie, Ryan WS Wee ... Andrew F MacAskill
    Amygdala input to ventral hippocampus is both excitatory and inhibitory, and the balance of these two projections controls the formation of place preference via differential innervation of each hippocampal output population.
    1. Cell Biology

    Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors

    Dawei Wang, Zuodong Ye ... Jianbo Yue
    CapZ controls actin filament density around immature early endosomes via its C-terminal domain to facilitate the homotypic fusion of the endocytic vesicles, and it functions as a scaffold protein via its N-terminal domain to recruit RAB5 effectors to early endosomes.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    EGFR transactivates RON to drive oncogenic crosstalk

    Carolina Franco Nitta, Ellen W Green ... Diane S Lidke
    Unidirectional crosstalk occurs between signaling competent EGFR dimers activating RON within heteromeric complexes at the plasma membrane.
    1. Cell Biology
    2. Neuroscience

    Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes

    Angela Kim, Jakob G Knudsen ... Linford JB Briant
    A novel process by which counter-regulatory glucagon release is regulated in both mouse and human.