Browse our latest research

Page 713 of 1,744
    1. Cell Biology
    2. Developmental Biology

    DAAM mediates the assembly of long-lived, treadmilling stress fibers in collectively migrating epithelial cells in Drosophila

    Kristin M Sherrard, Maureen Cetera, Sally Horne-Badovinac
    Stress fibers with multiple adhesions along their lengths and treadmilling dynamics may help migrating epithelial cells maintain a linear trajectory and thereby reinforce their collective motility.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Pathway dynamics can delineate the sources of transcriptional noise in gene expression

    Lucy Ham, Marcel Jackson, Michael PH Stumpf
    There are fundamental limits to what can be learned about the origins of transcriptional noise from gene expression data alone, which can be overcome by simultaneously quantifying the abundances of linked molecular species.
    1. Developmental Biology
    2. Evolutionary Biology

    Biomarkers in a socially exchanged fluid reflect colony maturity, behavior, and distributed metabolism

    Sanja M Hakala, Marie-Pierre Meurville ... Adria C LeBoeuf
    Socially exchanged fluids passed mouth-to-mouth in ant colonies contain protein signatures of colony maturity and individual behavioral role, indicating that this fluid may underlie a distributed metabolism that functions over the scale of the colony.
    1. Microbiology and Infectious Disease

    Modeling hepatitis C virus kinetics during liver transplantation reveals the role of the liver in virus clearance

    Louis Shekhtman, Miquel Navasa ... Harel Dahari
    Very frequent viral kinetics in liver transplant patients reveals that the liver is not only the source of hepatitis C virus (HCV) production, but also plays a major role in extracellular HCV clearance.
    1. Developmental Biology
    2. Genetics and Genomics

    Quantitative spatial and temporal assessment of regulatory element activity in zebrafish

    Shipra Bhatia, Dirk Jan Kleinjan ... Wendy A Bickmore
    A new method for quantitative assessment of altered regulatory potential of human enhancers bearing disease-associated mutations using live imaging in zebrafish embryos.
    1. Neuroscience

    A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation

    Harvey Perez, May F Abdallah ... Paul J Mathews
    Progressive changes in Purkinje neuron perturbations and overall cerebellar atrophy correlate for the first time with the development of an overt loss of motor function in a novel mouse model of Ataxia Telangiectasia.
    1. Medicine
    2. Neuroscience

    Neural basis for regulation of vasopressin secretion by anticipated disturbances in osmolality

    Angela Kim, Joseph C Madara ... Bradford B Lowell
    Two non-overlapping neural circuits that involve the lamina terminalis and arcuate nucleus of hypothalamus independently drive feedforward anticipatory suppression and activation of vasopressin neurons by drinking and feeding, respectively.
    1. Neuroscience

    Distinct higher-order representations of natural sounds in human and ferret auditory cortex

    Agnès Landemard, Célian Bimbard ... Yves Boubenec
    Auditory representations of natural sounds are similar in primary auditory cortex of ferrets and humans, but diverge sharply in non-primary areas for speech and music sounds.
    1. Cell Biology
    2. Developmental Biology

    Correct regionalization of a tissue primordium is essential for coordinated morphogenesis

    Yara E Sánchez-Corrales, Guy B Blanchard, Katja Röper
    During the morphogenesis of the tubes of the salivary glands in the fly embryo, a correct regionalization of the flat epithelial primordium by upstream transcription factors is key to drive coordinated changes in cell behavior.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells

    Sarah G Swygert, Dejun Lin ... Toshio Tsukiyama
    Using a yeast model of quiescence, it was demonstrated that dramatic changes in local chromatin fiber folding can occur under physiological conditions to regulate cellular processes.