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Delivery of auditory triggers as unique slow waves-targeting approach yields efficient, stable, and precise modulation of slow-wave activity in rats.

The current findings address the redox regulation of hypoxia inducible factor 1α (HIF1α) stability in hypoxia by showing that cytosolic, mitochondrial or lipid ROS are not necessary for HIF1α stabilization in hypoxia.

Lineage tracing and genetic experiments resolve a long-standing controversy by showing that retinoic acid signaling is active in cardiomyocytes, both during development and after myocardial infarction, and protects damaged hearts from apoptosis.

The discovery and development of a feline skin commensal bacterium for bacteriotherapy against skin disease, that could benefit patients due to established low cytotoxicity, broad-spectrum antimicrobial activity and anti-inflammatory activity.

Estimating fine-scale spatiotemporal patterns of Plasmodium falciparum transmission showed an association between entomological inoculation rate and parasite prevalence that emphasizes the value of both measures in malaria surveillance.

Harmful genetic variants at mendelian disease genes slow down adaptation, by interfering with the spread of adaptive variants in a population.

Lesions to the anterior-medio-dorsal thalamus cause widespread behavioral impairments across multiple cognitive domains, suggesting that thalamic hubs are critical for interconnecting diverse cognitive processes.

Postnatal, postsynaptic loss of FMRP specifically weakens callosal synaptic inputs onto L2/3 pyramidal neurons, in requirement ofnormal sensory experience, through downregulating AMPA receptor transmission and without affecting local synaptic inputs during cortical circuit development.

Senescent cells accumulate in the fracture callus and a reduction in the number of these cells accelerates fracture healing in mice.

The nutrient composition of food alters both the size of gut epithelial cells and the ability of the stem cell niche to control tissue turnover, resulting in changes in size at the organ level.