Browse our latest research

Page 803 of 1,737
    1. Neuroscience

    Songbirds can learn flexible contextual control over syllable sequencing

    Lena Veit, Lucas Y Tian ... Michael S Brainard
    Songbirds can use arbitrary visual cues to immediately, flexibly and adaptively control syntax of learned song vocalizations in a manner that parallels human cognitive control over syllable sequencing in speech.
    1. Genetics and Genomics
    2. Neuroscience

    Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology

    Eric N Anderson, Andrés A Morera ... Udai Bhan Pandey
    Traumatic injury leads to functional defects in nucleocytoplasmic transport and TDP-43 pathology in multiple model systems.
    1. Computational and Systems Biology
    2. Plant Biology

    An ABA-GA bistable switch can account for natural variation in the variability of Arabidopsis seed germination time

    Katie Abley, Pau Formosa-Jordan ... James CW Locke
    Arabidopsis shows extensive genetic diversity in germination time distributions, which can be explained by the underlying ABA/GA network functioning as a noisy bistable switch.
    1. Epidemiology and Global Health
    2. Medicine

    Mapping the endemicity and seasonality of clinical malaria for intervention targeting in Haiti using routine case data

    Ewan Cameron, Alyssa J Young ... Katherine E Battle
    A demonstration of the power of routine case data and statistical modelling to guide the allocation of anti-malarial interventions in a resource-constrained setting.
    1. Cancer Biology
    2. Cell Biology

    A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma

    Alvaro Gonzalez Rajal, Kamila A Marzec ... Andrew Burgess
    Platinum chemotherapy resistance is a complex process involving multiple signalling pathways and a novel, non-genetic, cell cycle-dependent mechanism that promotes tumour regrowth and highlights potential complications for combination therapies in human lung adenocarcinoma.
    1. Neuroscience

    Enhanced excitability of cortical neurons in low-divalent solutions is primarily mediated by altered voltage-dependence of voltage-gated sodium channels

    Briana J Martiszus, Timur Tsintsadze ... Stephen M Smith
    External calcium regulates neuronal excitability via its actions on voltage-gated sodium channels but not by regulating NALCN via the calcium-sensing receptor.
    1. Medicine
    2. Neuroscience

    Recovery of consciousness and cognition after general anesthesia in humans

    George A Mashour, Ben JA Palanca ... Max B Kelz
    Cognitive reconstitution after pharmacologic unconsciousness is an extended process, executive function is more robust than expected, and the healthy human brain is resilient to the effects of deep general anesthesia.
    1. Ecology
    2. Microbiology and Infectious Disease

    A novel ATP dependent dimethylsulfoniopropionate lyase in bacteria that releases dimethyl sulfide and acryloyl-CoA

    Chun-Yang Li, Xiu-Juan Wang ... Yu-Zhong Zhang
    A novel dimethylsulfoniopropionate lyase was identified, which catalyzes dimethyl sulfide releasing by a new mechanism and is found in several bacterial lineages, revealing its important roles in global sulfur cycling.
    1. Cancer Biology
    2. Cell Biology

    PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR

    Allen T Yu, Carmen Berasain ... David L Spector
    PHAROH lncRNA is upregulated in hepatocellular carcinoma and functions by sequestering the translational suppressor TIAR via a 71 nucleotide hairpin to regulate c-MYC translation.
    1. Neuroscience

    Dopamine differentially modulates the size of projection neuron ensembles in the intact and dopamine-depleted striatum

    Marta Maltese, Jeffrey R March ... Nicolas X Tritsch
    In addition to modulating firing rates, the neurotransmitter dopamine exerts a strong influence on the overall number of neurons in striatum that are recruited during behavior.