Browse our latest research

Page 804 of 1,737
    1. Genetics and Genomics
    2. Medicine

    A Mendelian randomization study of the role of lipoprotein subfractions in coronary artery disease

    Qingyuan Zhao, Jingshu Wang ... Daniel J Rader
    High-density lipoprotein (HDL) subfraction traits appear to have heterogeneous effects on coronary artery disease, giving support to the HDL function hypothesis.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection

    Tania Lebratti, Ying Shiang Lim ... Haina Shin
    Type I IFN is a key determinant of pathogenic neutrophil activity and drives tissue pathology through modulation of IL-18 levels during genital HSV infection.
    1. Medicine

    Development and validation of a nomogram to better predict hypertension based on a 10-year retrospective cohort study in China

    Xinna Deng, Huiqing Hou ... Haijiang Wu
    A developed and validated nomogram better predicts the risk of hypertension based on a 10-year retrospective cohort study in China.
    1. Microbiology and Infectious Disease

    4-Hydroxy-2-nonenal antimicrobial toxicity is neutralized by an intracellular pathogen

    Hannah Tabakh, Adelle P McFarland ... Joshua J Woodward
    The aldehyde 4-hydroxy-2-nonenal is a novel component of the host antimicrobial reactive oxygen burst, and the bacterium Listeria monocytogenes encodes genes specifically for its detoxification.
    1. Ecology
    2. Evolutionary Biology

    Inbreeding in a dioecious plant has sex- and population origin-specific effects on its interactions with pollinators

    Karin Schrieber, Sarah Catherine Paul ... Elisabeth Johanna Eilers
    Inbreeding compromises floral traits and reduces pollinator visitation rates disproportionally in female relative to male individuals in a dioecious plant and may thus interfere with the equilibrium of a complex co-evolutionary plant-insect relationship.
    1. Cell Biology
    2. Physics of Living Systems

    Flagellar energetics from high-resolution imaging of beating patterns in tethered mouse sperm

    Ashwin Nandagiri, Avinash Satish Gaikwad ... Ranganathan Prabhakar
    Calculations of flagellar energetics from beating patterns in sperm reveal that internal dissipation by dynein motors and other passive structures within the flagellum significantly exceeds external hydrodynamic dissipation.
    1. Neuroscience

    An excitatory lateral hypothalamic circuit orchestrating pain behaviors in mice

    Justin N Siemian, Miguel A Arenivar ... Yeka Aponte
    A small population of lateral hypothalamic neurons detects pain and can be activated to suppress pain-related behavioral adaptations and the unpleasantness associated with pain in mice.
    1. Neuroscience

    Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1

    Vincent Robert, Ludivine Therreau ... Rebecca Ann Piskorowski
    Input conveying social novelty information from the hypothalamus controls hippocampal activity by recruiting a novel inhibitory circuit in hippocampal area CA2.
    1. Neuroscience

    Distinct protocerebral neuropils associated with attractive and aversive female-produced odorants in the male moth brain

    Jonas Hansen Kymre, XiaoLan Liu ... Xi Chu
    Electrophysiological and morphological identification of individual pheromone projection neurons in male moth reveals a coding system for optimizing mate search strategy, including computation of three female-produced signals in distinct protocerebral regions.
    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo

    Gerald Willimsky, Christin Beier ... Peter M Kloetzel
    Analysis of neo-splicetope-specific T cell responses strongly questions the idea that in vitro proteasome-catalyzed peptide splicing reaction simulates the in vivo situation with the same high fidelity as the in vitro generation of non-spliced epitopes.