Browse our latest research

Page 830 of 1,838
    1. Neuroscience

    Individual history of winning and hierarchy landscape influence stress susceptibility in mice

    Katherine B LeClair, Kenny L Chan ... Scott J Russo
    Socially dominant mice, unlike subordinates, are protected from displaying a common stress-associated behavioral deficit, social avoidance, following exposure to multiple kinds of chronic stress.
    1. Ecology

    Linking spatial self-organization to community assembly and biodiversity

    Bidesh K Bera, Omer Tzuk ... Ehud Meron
    A trait-based model of dryland vegetation uncovers the roles of spatial self-organization in maintaining biodiversity in a changing climate and offers novel ways of managing ecosystems at risk.
    1. Plant Biology

    SUMOylation contributes to proteostasis of the chloroplast protein import receptor TOC159 during early development

    Sonia Accossato, Felix Kessler, Venkatasalam Shanmugabalaji
    SUMOylation contributes to the fine-tuning of the proteostatic equilibrium of essential chloroplast protein import receptor TOC159 at early plant development.
    1. Cell Biology
    2. Plant Biology

    Crosstalk between the chloroplast protein import and SUMO systems revealed through genetic and molecular investigation in Arabidopsis

    Samuel James Watson, Na Li ... R Paul Jarvis
    The small ubiquitin-like modifier system directly regulates components of the chloroplast protein import apparatus, that is, TOC proteins, to control chloroplast biogenesis and plant development.
    1. Developmental Biology
    2. Neuroscience

    Activity-dependent modulation of synapse-regulating genes in astrocytes

    Isabella Farhy-Tselnicker, Matthew M Boisvert ... Nicola J Allen
    RNA sequencing and genetic mouse models reveal that transcriptional changes to astrocytes in the developing cortex are not intrinsic but influenced by their environment and determine that expression of astrocyte synapse-regulating genes and neuronal synaptogenesis is modulated by ongoing astrocyte-neuron communication.
    1. Neuroscience

    Convergent and divergent brain structural and functional abnormalities associated with developmental dyslexia

    Xiaohui Yan, Ke Jiang ... Fan Cao
    Convergent structural and functional brain deficits associated with dyslexia were found in left superior temporal gyrus across languages, however, language-specific deficits were also identified.
    1. Cancer Biology

    Lipid droplets and ferritin heavy chain: a devilish liaison in human cancer cell radioresistance

    Luca Tirinato, Maria Grazia Marafioti ... Joao Seco
    Lipid Droplet accumulation is a fingerprint shared by different human cancer radioresistant cells and their biogenesis strongly depend on FTH1 presence.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A modified fluctuation assay reveals a natural mutator phenotype that drives mutation spectrum variation within Saccharomyces cerevisiae

    Pengyao Jiang, Anja R Ollodart ... Kelley Harris
    Certain mutational signatures vary in their contribution to genetic variation across the yeast phylogeny due to genetically encoded natural mutator phenotypes whose activity can be directly measured in the lab.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

    Mona Seifert, Subhas C Bera ... David Dulin
    High-throughput and ultra-stable magnetic tweezers reveal that Remdesivir induces a long-lived backtrack pause upon incorporation by the coronavirus polymerase, and SARS-CoV-2 is able to evade interferon-induced antiviral ddhCTP.
    1. Neuroscience

    Circadian regulation of vertebrate cone photoreceptor function

    Jingjing Zang, Matthias Gesemann ... Stephan CF Neuhauss
    Circadian expression of cone visual transduction genes and corresponding proteins correlates with circadian changes in photoresponse kinetics and visual behavior, linking circadian gene expression with physiological and behavioral rhythmicity.