Katherine B LeClair, Kenny L Chan ... Scott J Russo
Socially dominant mice, unlike subordinates, are protected from displaying a common stress-associated behavioral deficit, social avoidance, following exposure to multiple kinds of chronic stress.
A trait-based model of dryland vegetation uncovers the roles of spatial self-organization in maintaining biodiversity in a changing climate and offers novel ways of managing ecosystems at risk.
Sonia Accossato, Felix Kessler, Venkatasalam Shanmugabalaji
SUMOylation contributes to the fine-tuning of the proteostatic equilibrium of essential chloroplast protein import receptor TOC159 at early plant development.
The small ubiquitin-like modifier system directly regulates components of the chloroplast protein import apparatus, that is, TOC proteins, to control chloroplast biogenesis and plant development.
Isabella Farhy-Tselnicker, Matthew M Boisvert ... Nicola J Allen
RNA sequencing and genetic mouse models reveal that transcriptional changes to astrocytes in the developing cortex are not intrinsic but influenced by their environment and determine that expression of astrocyte synapse-regulating genes and neuronal synaptogenesis is modulated by ongoing astrocyte-neuron communication.
Convergent structural and functional brain deficits associated with dyslexia were found in left superior temporal gyrus across languages, however, language-specific deficits were also identified.
Luca Tirinato, Maria Grazia Marafioti ... Joao Seco
Lipid Droplet accumulation is a fingerprint shared by different human cancer radioresistant cells and their biogenesis strongly depend on FTH1 presence.
Certain mutational signatures vary in their contribution to genetic variation across the yeast phylogeny due to genetically encoded natural mutator phenotypes whose activity can be directly measured in the lab.
High-throughput and ultra-stable magnetic tweezers reveal that Remdesivir induces a long-lived backtrack pause upon incorporation by the coronavirus polymerase, and SARS-CoV-2 is able to evade interferon-induced antiviral ddhCTP.
Jingjing Zang, Matthias Gesemann ... Stephan CF Neuhauss
Circadian expression of cone visual transduction genes and corresponding proteins correlates with circadian changes in photoresponse kinetics and visual behavior, linking circadian gene expression with physiological and behavioral rhythmicity.