Browse our latest research

Page 855 of 1,838
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

    Olivier Cochet-Escartin, Mete Demircigil ... Jean-Paul Rieu
    Cell assemblies can use environmental cues created by their own respiration, such as oxygen gradients, to collectively guide themselves to more favorable locations in a remarkably robust and long-lasting way.
    1. Neuroscience

    Understanding neural signals of post-decisional performance monitoring: An integrative review

    Kobe Desender, K Richard Ridderinkhof, Peter R Murphy
    A computationally explicit framework can explain post-decisional neural signals of performance monitoring.
    1. Developmental Biology

    Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling

    Ryo Hatori, Brent M Wood ... Thomas B Kornberg
    Delivery of Hedgehog, Decapentaplegic and Wingless to target cells in the Drosophila wing imaginal disc is regulated in both amount and destination, and is not dependent on constitutive release or uptake from a common pool.
    1. Neuroscience

    Perception of microstimulation frequency in human somatosensory cortex

    Christopher L Hughes, Sharlene N Flesher ... Robert A Gaunt
    Increasing microstimulation frequency in some regions of the human somatosensory cortex decreased the perceived intensity and evoked specific percepts, providing insight into cortical organization and sensory feedback approaches for brain–computer interfaces.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Single-cell analysis of mosquito hemocytes identifies signatures of immune cell subtypes and cell differentiation

    Hyeogsun Kwon, Mubasher Mohammed ... Ryan C Smith
    Single-cell RNA-seq analysis reveals an increased complexity of mosquito hemocytes, enabling the functional and molecular characterization of immune cell sub-populations in Anopheles gambiae.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome

    Isabelle J Marié, Lara Brambilla ... David E Levy
    Overlapping action of type I, II, and III interferons maintains microbiome homeostasis, prevents IL-17-driven myeloproliferative disease, and protects against inflammatory bowel disease.
    1. Microbiology and Infectious Disease

    Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection

    Mackenzie M Shipley, Vidya Mangala Prasad ... Julie M Overbaugh
    A bnAb derived from a case of HIV superinfection has distinct qualities from other HIV-specific bnAbs, including framework residues that contribute to neutralization breadth and a unique viral escape profile.
    1. Neuroscience

    Long-term stability of cortical ensembles

    Jesús Pérez-Ortega, Tzitzitlini Alejandre-García, Rafael Yuste
    Spontaneous and visually evoked neuronal ensembles in mouse visual cortex can last for weeks, potentially supporting the long-lasting representation of perceptions and memories.
    1. Developmental Biology

    Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway

    Hyae Yon Kweon, Mi-Ni Lee ... Gholson J Lyon
    Mice doubly deficient for Naa10 and Naa12 display embryonic lethality, with both enzymes compensating for each other with amino-terminal acetylation of proteins in mouse development.
    1. Structural Biology and Molecular Biophysics

    TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase

    Jing Xue, Yan Han ... Youxing Jiang
    Cryo-EM structure of human TMEM120A reveals that it is a coenzyme A-binding protein and is unlikely to function as a mechanosensitive channel as was recently proposed.