Browse our Insights

Page 4 of 103
    1. Biochemistry and Chemical Biology

    Support Proteins: Getting bacterial cells into shape

    Mrinmayee Bapat, Vani Pande, Pananghat Gayathri
    The conformational state of a structural protein in bacteria can vary, depending on the concentration level of potassium ions or the nucleotide bound to it.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Computational and Systems Biology

    Genetics: From mouse to human

    Arya Mani
    A deep analysis of multiple genomic datasets reveals which genetic pathways associated with atherosclerosis and coronary artery disease are shared between mice and humans.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Epidemiology and Global Health

    Sleep: Another benefit of regular sleep

    Tianyi Huang
    A large observational study has found that irregular sleep-wake patterns are associated with a higher risk of overall mortality, and also mortality from cancers and cardiovascular disease.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Transcription: A hub of activity

    Virginia L Pimmett, Mounia Lagha
    Imaging experiments reveal the complex and dynamic nature of the transcriptional hubs associated with Notch signaling.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Cell Biology

    Trans-Golgi Network: Sorting secretory proteins

    Anup Parchure, Julia von Blume
    A receptor protein called TGN46 has an important role in sorting secretory proteins into vesicles going to different destinations inside cells.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Antibody Specificity: A strong case for third-party testing

    Fridtjof Lund-Johansen
    A strategy to identify high-quality commercially available antibodies for research reveals extensive use of non-specific antibodies and offers solutions for future large-scale testing.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Neuroscience

    Anesthesia: Putting early sensory neurons to sleep

    Julia Fadjukov, Gregory Schwartz
    Neurons that transmit information from the retina to other parts of the brain are more affected by anesthesia than previously thought.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Evolutionary Biology
    2. Neuroscience

    Cerebellum: Folding into shape

    Héloïse de Vareilles
    A new computational tool provides insights into the structure of the cerebellum in mammals.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Medicine

    Cardiology: A new strategy for cardiac protection

    Esmaa Bouhamida, Hina W Chaudhry
    It may be possible to treat cardiac hypertrophy and injury by using drugs that inhibit a protein called SIRT2.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Evolutionary Biology

    Genetics: A colourful duplication

    Violaine Llaurens
    A genetic duplication event during evolution allowed male wood tiger moths to have either yellow or white patterns on their wings.
    Insight
    Formats available:
    • HTML
    • PDF