Browse our Research Articles

Page 233 of 1,392
    1. Epidemiology and Global Health

    Understanding disruptions in cancer care to reduce increased cancer burden

    Kia L Davis, Nicole Ackermann ... Vetta L Sanders Thompson
    Many people canceled cancer screening and cancer care appointments during the pandemic, but cancer prevention and control practitioners must proactively facilitate their return to care to avoid widening cancer health disparities.
    1. Ecology
    2. Evolutionary Biology

    Novel pathogen introduction triggers rapid evolution in animal social movement strategies

    Pratik Rajan Gupte, Gregory F Albery ... Franz J Weissing
    The introduction of infectious pathogens to a simulated animal population leads to rapid evolutionary transitions in how individuals move in a social context, with distinct movement morphs evolved that make trade-offs between sociality and infection risk.
    1. Neuroscience

    Subcortico-amygdala pathway processes innate and learned threats

    Valentina Khalil, Islam Faress ... Sadegh Nabavi
    The subcortical amygdala pathway, which has been traditionally associated with learning threats, is also required for processing an innate threat.
    1. Cancer Biology
    2. Microbiology and Infectious Disease

    Evidence for virus-mediated oncogenesis in bladder cancers arising in solid organ transplant recipients

    Gabriel J Starrett, Kelly Yu ... Eric A Engels
    Nearly half of bladder cancers of solid organ transplant recipients harbor papillomaviruses or polyomaviruses, with many tumors showing evidence of clonal viral integration and viral oncogene effects on tumor gene expression patterns.
    1. Cell Biology
    2. Immunology and Inflammation

    FAM76B regulates NF-κB-mediated inflammatory pathway by influencing the translocation of hnRNPA2B1

    Dongyang Wang, Xiaojing Zheng ... Haibin Xia
    Genetic and biochemical analyses in vitro and in vivo reveal how the novel protein FAM76B regulates inflammation.
    1. Immunology and Inflammation
    2. Medicine

    Hypoxia-inducible factor 1 signaling drives placental aging and can provoke preterm labor

    Erin J Ciampa, Padraich Flahardy ... Samir M Parikh
    The role of placental aging and metabolic stress in driving labor onset is demonstrated, with a novel mouse model of preterm labor in which injection of a prolyl hydroxylase inhibitor stabilizes placental hypoxia-inducible factor 1 and significantly shortens gestational length.
    1. Developmental Biology

    Identification of quiescent FOXC2+ spermatogonial stem cells in adult mammals

    Zhipeng Wang, Cheng Jin ... Wei Song
    The FOXC2+ quiescent spermatogonial stem cells are essential for the maintenance of spermatogenesis.
    1. Developmental Biology
    2. Evolutionary Biology

    Coronary artery established through amniote evolution

    Kaoru Mizukami, Hiroki Higashiyama ... Hiroki Kurihara
    During the evolution of amniotes, the transformation of branchial arches coincided with the drastic remodeling of the ancestral extrinsic cardiac arteries, giving rise to novel ventricular coronary arteries that are unique to amniotes.
    1. Neuroscience

    Functional imaging of conduction dynamics in cortical and spinal axons

    Milos Radivojevic, Anna Rostedt Punga
    Reconstruction of axonal morphologies based on extracellular action potentials enables label-free electrical visualization of axonal conduction trajectories, providing a noninvasive method for functional profiling of cortical and spinal axons.
    1. Genetics and Genomics

    Ether lipid biosynthesis promotes lifespan extension and enables diverse pro-longevity paradigms in Caenorhabditis elegans

    Lucydalila Cedillo, Fasih M Ahsan ... Alexander A Soukas
    Increased production of ether lipids is required to extend lifespan in response to metformin, phenformin, and multiple, distinct, longevity-promoting manipulations, illuminating the possibility that raising ether lipid levels represents a new therapeutic strategy to support healthy aging.