Browse our Research Articles

Page 458 of 1,383
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Evolution of host-microbe cell adherence by receptor domain shuffling

    EmilyClare P Baker, Ryan Sayegh ... Matthew F Barber
    Rapid evolution and gene conversion of a primate cell surface receptor family blocks recognition by pathogenic bacteria.
    1. Neuroscience

    Slowly evolving dopaminergic activity modulates the moment-to-moment probability of reward-related self-timed movements

    Allison E Hamilos, Giulia Spedicato ... John A Assad
    Dynamic dopaminergic signaling modulates the timing of reward-related movements by tuning the moment-to-moment probability of their onset.
    1. Neuroscience

    Respiratory alkalosis provokes spike-wave discharges in seizure-prone rats

    Kathryn A Salvati, George MPR Souza ... Mark P Beenhakker
    Respiratory alkalosis recruits the midline thalamus to provoke absence seizures.
    1. Neuroscience

    Rapid odor processing by layer 2 subcircuits in lateral entorhinal cortex

    Sebastian H Bitzenhofer, Elena A Westeinde ... Jeffry S Isaacson
    Electrophysiological recordings reveal how cells encode odor identity and intensity in the lateral entorhinal cortex of awake mice.
    1. Epidemiology and Global Health

    Anopheles salivary antigens as serological biomarkers of vector exposure and malaria transmission: A systematic review with multilevel modelling

    Ellen A Kearney, Paul A Agius ... Freya JI Fowkes
    A systematic review with multilevel modelling quantified the positive association between human antibodies to Anopheles salivary proteins with Anopheles-human biting rate and epidemiological measures of malaria transmission, highlighting their potential as a tool to measure vector exposure and malaria transmission.
    1. Genetics and Genomics

    Genetically engineered insects with sex-selection and genetic incompatibility enable population suppression

    Ambuj Upadhyay, Nathan R Feltman ... Michael Smanski
    Two distinct genetic biocontrol methods work synergistically to yield a novel approach in the fight against pest organisms.
    1. Immunology and Inflammation

    Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

    Noella Lopes, Nicolas Boucherit ... Magali Irla
    Self-reactive CD4+ thymocytes have a broad impact on the composition of medullary thymic epithelial cell (mTEC) subsets by acting upstream of Aire+ mTECs, which conditions the induction of T-cell tolerance.
    1. Cell Biology

    P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian β-cell failure

    Biliana Marcheva, Benjamin J Weidemann ... Joseph Bass
    A genetically sensitized drug screen identifies a circadian diabetes target and establishes a novel discovery pathway to treat β-cell failure.
    1. Physics of Living Systems

    Cellular organization in lab-evolved and extant multicellular species obeys a maximum entropy law

    Thomas C Day, Stephanie S Höhn ... Peter J Yunker
    The distributions of cellular neighborhood volumes in two very different multicellular species - snowflake yeast and Volvox carteri - are found to obey a common functional form arising from maximum entropy consideration, despite great differences in their cell division processes.
    1. Neuroscience

    Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency

    Andres De La Rossa, Marine H Laporte ... Jean-Claude Martinou
    Glutamatergic neurons lacking the mitochondrial pyruvate carrier show reduced M-type potassium channel activity and hyperexcitability upon intense firing.